25245-39-0Relevant academic research and scientific papers
2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d] pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance
Gangjee, Aleem,Namjoshi, Ojas A.,Keller, Staci N.,Smith, Charles D.
experimental part, p. 4355 - 4365 (2011/08/09)
Gangjee et al. recently reported a novel series of 2-amino-4-methyl-5- phenylethyl substituted-7-benzyl-pyrrolo[2,3-d]pyrimidines, some of which exhibited two digit nanomolar antitumor and antimitotic activity and were not subject to P-glycoprotein (Pgp)
Quinol fatty alcohols as promoters of axonal growth
Hanbali, Mazen,Vela-Ruiz, Marta,Bagnard, Dominique,Luu, Bang
, p. 2637 - 2640 (2007/10/03)
The synthesis of three series of quinol fatty alcohols (QFAs) and their biological activities on the promotion of axonal growth are described. Interestingly, the 15-(2,5-dimethoxyphenyl)pentadecan-1-ol, the QFA bearing 15 carbon atoms on the side chain (n = 15), shows the most potent promotion of axonal growth in the presence of both permissive and non-permissive naturally occurring substrates such as Sema3A and myelin proteins.
Synthetic studies on the flavone derivatives. XIII. Synthesis of flavones with tetramethoxyl groups in ring B
Iinuma,Tanaka,Matsuura
, p. 3354 - 3360 (2007/10/02)
2',3',4',5,5',6,7,8-Octamethoxy- (Ia) and 2',3',4',5,5',6,7-heptamethoxyflavone (IIa) and their position isomers substituted with tetramethoxyl groups in ring B were synthesized to confirm the structures of agehoustin A and agehoustin B isolated from Ageratum houstonianum. The characteristics of the synthesized flavones were investigated by spectroscopic methods.
SYNTHESIS OF UBIQUINONE AND MENAQUINONE ANALOGUES BY OXIDATIVE DEMETHYLATION OF ALKENYLHYDROQUINONE ETHERS WITH ARGENTIC OXIDE OR CERIC AMMONIUM NITRATE IN THE PRESENCE OF 2,4,6-PYRIDINE-TRICARBOXYLIC ACID
Syper, L.,Kloc, K.,Mlochowski, J.
, p. 123 - 129 (2007/10/02)
It was found that alkenylhydroquinone ethers demethylated with argentic oxide or ceric ammonium nitrate in the presence of 2,4,6-pyridinetricarboxylic acid as a catalyst and afforded ubiquinone-2, menaquinone-2 and their analogs in yields of 53 to 89 percent.The new approach to the synthesis of starting alkenylhydroquinone ethers as well as 2,4,6-pyridinetricarboxylic acid and its derivatives has been reported.
