252579-98-9Relevant articles and documents
Enantioselective synthesis of α,β-substituted β-amino acids
Agami, Claude,Cheramy, Sandrine,Dechoux, Luc,Melaimi, Mohand
, p. 195 - 200 (2007/10/03)
Chiral derivative 3 was shown to be a precursor of α and β-substituted β-amino acids as well as α,β-disubstituted β-amino acids. The key steps of the procedure are a diastereoselective alkylation of synthon 3 by organocuprates reagents and a diastereoselective alkylation of the alkylated adduct.