25258-08-6Relevant academic research and scientific papers
Synthesis of cationic glucosamino nucleic acids for stabilizing oligonucleotides
Kitamura, Yoshiaki,Moribe, Shuichi,Kitade, Yukio
, p. 3174 - 3176 (2018)
Glucosamino nucleic acids (GANAs) bearing a β-N-glycoside bond between carbon 1 of the glucosamine and the nucleobase nitrogen were synthesized and incorporated into oligonucleotides (4′,6′-GANA and 3′,6′-GANA). The thermal stability of oligonucleotide duplexes containing the GANA zwitterionic nucleotides was also investigated.
