252679-85-9Relevant academic research and scientific papers
The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives
Smith, David G.,Gribble, Andrew D.,Haigh, David,Ife, Robert J.,Lavery, Patrick,Skett, Peter,Slingsby, Brian P.,Stacey, Rachel,Ward, Robert W.,West, Andrew
, p. 3137 - 3142 (2007/10/03)
Aryl hydroxylamine derivatives have been synthesised that are some of the most potent inhibitors of hCMV protease prepared to date (IC50 14-60 nM). Mass spectrometry studies indicate that oxazinone derived hydroxylamines inhibit the enzyme by a
