25284-40-6

Upstream product

• 766-77-8 Dimethylphenylsilane 
• 107-13-1 acrylonitrile 
• 557-21-1 zinc(II) cyanide 
• 1125-26-4 dimethylphenylvinylsilane 

Downstream Products

• 53153-69-8 (E)-2-Methyl-3-phenyl-but-2-enenitrile 
• 1197-33-7 2-methyl-3-phenyl-acrylonitrile 
• 1856-66-2 (2Z,4Z)-2,3-Dimethyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-penta-2,4-dienenitrile 

Relevant academic research and scientific papers

Generation of a reducing reagent from Copper(I) salt and hydrosilane. New practical method for conjugate reduction

Hydride transfer from a hydrosilane to a copper(I) salt is reported. The silicon group of hydrosilanes was smoothly replaced by copper(I) chloride in DMI to give the corresponding metal hydride complex of copper(I). This transformation was applied to conjugate reduction of α,β-unsaturated compounds with a hydrosilane mediated by copper(I) chloride.

Preparation method of alkyl nitrile compound

The invention discloses a preparation method of an alkyl nitrile compound. Specifically, the preparation method comprises the following step: in an organic solvent, in the presence of a protective gasand under the action of a catalyst, carrying out a reduction reaction as shown in the specification on olefin as shown in a formula I, a cyanation reagent and water, wherein the alkyl nitrile compound 1 is a compound II and/or a compound III. The preparation method provided by the invention is mild in condition, can realize hydrocyanation of olefin more safely and efficiently, and has good substrate universality and functional group compatibility.

Markovnikov-selective hydrosilylation of electron-deficient alkenes with arylsilanes catalyzed by mono(phosphine)palladium(0)

Markovnikov-selective hydrosilylation of electron-deficient alkenes with HSiPh3 is catalyzed by a mono(phosphine)palladium(0) complex, Pd(η2:η2-C6H10O)(PMe3) (1a). The hydrosilylation of acrylonitrile with HSiPh3 at 30 °C proceeds to completion within 40 min in the presence of 5 mol % of 1a. The complex 1a also shows the catalytic activity for the hydrosilylation with mono- and diarylsilanes and monochlorosilane such as HSiPhMe2, HSiPh2Me, and HSiClMe2. The hydrosilylation using para-substituted styrenes clearly shows the electron-withdrawing substituent promoting the reaction. Mechanistic studies indicate that the reaction is proceeding by a Chalk-Harrod mechanism with the reductive elimination of an (alkyl)(silyl)palladium(II) intermediate being the rate-determining step.

Rhenium-mediated dehydrogenative silylation and highly regioselective hydrosilylation of nitrile substituted olefins

The rhenium (I) complex [Re(CH3CN)3Br 2(NO)] catalyzes the homogeneous hydrosilylation of a variety of substituted acrylonitriles, which were converted into the corresponding silyl-substituted alkanes with high regioselectivity of up to 94%. The products were analyzed by 1H NMR and GC-MS. A rhenium specific mechanism is proposed for the hydrosilylation of olefins.