252857-23-1

Basic information

• Product Name: (8-hydroxy-1-oxa-4-aza-spiro[4.5]dec-4-yl)-phenyl-methanone
• Synonyms: (8-hydroxy-1-oxa-4-aza-spiro[4.5]dec-4-yl)-phenyl-methanone
• CAS NO: 252857-23-1
• Molecular Weight: 261.321
• Mol File: 252857-23-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (8-hydroxy-1-oxa-4-aza-spiro[4.5]dec-4-yl)-phenyl-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (8-hydroxy-1-oxa-4-aza-spiro[4.5]dec-4-yl)-phenyl-methanone(252857-23-1)
• EPA Substance Registry System: (8-hydroxy-1-oxa-4-aza-spiro[4.5]dec-4-yl)-phenyl-methanone(252857-23-1)

Safety Data

• Hazardous Substances Data: 252857-23-1(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 177-04-8 1-oxa-4-azaspiro[4.5]decane 
• 70971-45-8 4-benzoyl-1-oxa-4-aza-spiro[4.5]decane 

Downstream Products

• 13482-22-9 4-hydroxycyclohexanone 

Relevant articles and documents

The concept of docking/protecting groups in biohydroxylation

A general principle for biohydroxylation, in which time-consuming screening and enrichment techniques are avoided, is demonstrated by the introduction of a docking/protecting group into the substrate. This facilitates acceptance by the microorganism and allows the use of a narrow range of microorganisms, for example Beauveria bassiana ATTC7159 (B.b.), for the hydroxylation of compounds with diverse structures. After the biohydroxylation, the docking/protecting group is removed (see scheme).