252864-96-3Relevant academic research and scientific papers
Asymmetric synthesis of 9-alkyl-2-benzyl-6,7-benzomorphans: Characterization as novel σ receptor ligands
Carroll, F. Ivy,Bai, Xu,Dehghani, Ali,Mascarella, S. Wayne,Williams, Wanda,Bowen, Wayne D.
, p. 4621 - 4629 (2007/10/03)
A convenient enantioselective synthesis of (1R,5R,9R)- and (1S,5S,9S)-9- alkyl-2-benzyl-6,7-benzomorphans (2a-c) which starts with naphthaldehyde is described. These compounds were designed to gain additional information on the structure-σ binding relatio
A novel asymmetric synthesis of 3-Benzyl-1,2,3,4,5,6-hexahydro-11-alkyl-2,6-methano-3- benzazocines
Bai,Mascarella,Bowen,Carroll
, p. 2401 - 2402 (2007/10/02)
9-Alkyl 6,7-benzomorphans (1,2,3,4,5,6-hexahydro-11-alkyl-2,6-methano-3-benzazocines) are important selective ligands of sigma receptor sites; their asymmetric synthesis starting with (1 R,2R)- or (1S,2S)-1-hydroxymethyl-2-alkyl-1,2-dihydronaphthalene is
