252973-46-9Relevant academic research and scientific papers
(1H-benzo[d][1,2,3]triazol-1-yl)methanol: An efficient bidentate ligand for copper catalyzed S-arylation of thiols
Jhaa, Rajeev Ranjan,Choudharya, Deepak,Verma, Akhilesh K.
, p. 451 - 458 (2019/01/21)
An operationally simple, palladium-free synthetic protocol for thio-arylation using 0.5 mol % CuI and 1 mol % (1H-benzo[d][1,2,3]triazol-1-yl)methanol as ligand is described. The ligand was found to be cheap, thermally stable, easy to synthesize, show simplicity in use and wide use in coupling reactions. Appropriately, the donor ability of the N=N bond of the benzotriazole ring and lone pair of electrons on the hydroxy group increases the bidentate ability of the ligand. Using this protocol, we have shown that a variety of aryl sulfides that can be synthesized in excellent yields from readily available aryl halide and thiols.
A general and efficient CuI/BtH catalyzed coupling of aryl halides with thiols
Verma, Akhilesh Kumar,Singh, Jaspal,Chaudhary, Ritu
, p. 7199 - 7202 (2008/03/11)
We report an exceptionally mild, general and efficient copper catalyzed cross coupling reaction of aryl bromides and thiols using 0.5 mol % CuI and 1 mol % benzotriazole. Experimental simplicity, generality, functional group tolerance and low cost of the catalyst are advantages of the protocol.
Solid-phase synthesis of diaryl sulfides: Direct coupling of solid-supported aryl halides with thiols using an insoluble polymer-supported reagent
Gendre, Fabrice,Yang, Mathieu,Diaz, Philippe
, p. 2719 - 2722 (2007/10/03)
(Chemical Equation Presented) Diaryl sulfides have been prepared by direct nickel(II)-catalyzed coupling of thiols with iodoaryl bound to SynPhase polystyrene lanterns in the presence of polymer-supported borohydride.
