25300-37-2

Basic information

• Product Name: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE
• Synonyms: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE;2-CHLORO-6-METHYLBENZENESULPHONYL CHLORIDE;6-Chloro-o-toluenesulfonylchoride;6-Chloro-o-toluenesulfonyl chloride;2-chloro-6-Methylbenzene-1-sulfonyl chloride
• CAS NO: 25300-37-2
• Molecular Formula: C₇H₆Cl₂O₂S
• Molecular Weight: 225.09
• Mol File: 25300-37-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 132-134°C 0,5mm
• Flash Point: 132-134°C/0.5mm
• Appearance: /
• Density: 1.459g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.5810
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Moisture Sensitive
• BRN: 2722659
• CAS DataBase Reference: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE(25300-37-2)
• EPA Substance Registry System: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE(25300-37-2)

Safety Data

• Statements: 20/21/22-34-36/37
• Safety Statements: 26-27-36/37/39
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 25300-37-2(Hazardous Substances Data)

Usage

Description

2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE is an organic chemical compound characterized by the presence of a chloro and methyl group attached to a benzene ring, with a sulfonyl chloride functional group. It is known for its reactivity and utility in various chemical reactions and synthesis processes.

Uses

Used in Pharmaceutical Industry:
2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE is used as a reagent for the synthesis of dihydropyridonesulfonamides, which are compounds that exhibit thrombin and trypsin inhibitory activity. These properties make them valuable in the development of medications targeting blood clotting disorders and other related conditions.

InChI:InChI=1/C7H6Cl2O2S/c1-5-3-2-4-6(8)7(5)12(9,10)11/h2-4H,1H3

Downstream Products

• 145979-28-8 O-isopropyl P-ethyl[[(2-methylphenyl)sulfonyloxy]methyl]phosphinate 
• 1215721-32-6 C₂₀H₂₄ClNO₃S 
• 1602577-81-0 N-(2-chloro-6-methylphenylsulfonyl)-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide 
• 90196-33-1 2-chloro-6-methyl-benzenesulphonamide 
• 1380229-06-0 2-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-6-methylbenzenesulfonamide 
• 1388804-86-1 N'-(2-chloro-6-methylbenzenesulfonyl)-4-methyl-3-[2-(3-quinolyl)ethynyl]benzohydrazide 
• 1361582-32-2 ethyl 2-(2-chloro-6-methylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-1-carboxylate 
• 1269500-07-3 C₂₂H₂₈ClN₃O₅S 
• 1258070-36-8 2-[[[(2-chloro-6-methyl-phenyl)sulfonyl]-methyl-amino]-methyl]-3H-benzoimidazole-4-carboxylic acid methyl ester 
• 1226949-67-2 (S)-4-(1-(3-(1-(2-chloro-6-methylphenylsulfonyl)pyrrolidin-2-yl)propylsulfonyl)piperidin-4-yloxy)pyridine 
• 1191240-21-7 (1-(2-chloro-6-methylphenylsulfonyl)piperidin-2-yl)methanol 
• 1198055-53-6 2-chloro-6-methyl-N-{1-[(4-methylpiperidin-1-yl)carbonyl]-3-phenylpropyl}benzenesulfonamide 
• 1186241-05-3 C₂₂H₃₀ClNO₄SSi 

Relevant articles and documents

Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists

The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.