25300-37-2

Basic information

• Product Name: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE
• Synonyms: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE;2-CHLORO-6-METHYLBENZENESULPHONYL CHLORIDE;6-Chloro-o-toluenesulfonylchoride;6-Chloro-o-toluenesulfonyl chloride;2-chloro-6-Methylbenzene-1-sulfonyl chloride
• CAS NO: 25300-37-2
• Molecular Formula: C₇H₆Cl₂O₂S
• Molecular Weight: 225.09
• Mol File: 25300-37-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 132-134°C 0,5mm
• Flash Point: 132-134°C/0.5mm
• Appearance: /
• Density: 1.459g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.5810
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Moisture Sensitive
• BRN: 2722659
• CAS DataBase Reference: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE(25300-37-2)
• EPA Substance Registry System: 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE(25300-37-2)

Safety Data

• Statements: 20/21/22-34-36/37
• Safety Statements: 26-27-36/37/39
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 25300-37-2(Hazardous Substances Data)

Usage

Description

2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE is an organic chemical compound characterized by the presence of a chloro and methyl group attached to a benzene ring, with a sulfonyl chloride functional group. It is known for its reactivity and utility in various chemical reactions and synthesis processes.

Uses

Used in Pharmaceutical Industry:
2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE is used as a reagent for the synthesis of dihydropyridonesulfonamides, which are compounds that exhibit thrombin and trypsin inhibitory activity. These properties make them valuable in the development of medications targeting blood clotting disorders and other related conditions.

InChI:InChI=1/C7H6Cl2O2S/c1-5-3-2-4-6(8)7(5)12(9,10)11/h2-4H,1H3

Downstream Products

• 1190971-04-0 2-chloro-N-cyclopropyl-N-(2-hydroxyethyl)-6-methyl-benzenesulfonamide 
• 1187963-92-3 4-(1-(2-Chloro-6-methylphenylsulfonyl)piperidin-2-yl)butanoic acid methyl ester 
• 1186241-05-3 C₂₂H₃₀ClNO₄SSi 
• 1602577-81-0 N-(2-chloro-6-methylphenylsulfonyl)-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamide 
• 90196-33-1 2-chloro-6-methyl-benzenesulphonamide 
• 1380229-06-0 2-chloro-N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-6-methylbenzenesulfonamide 
• 1388804-86-1 N'-(2-chloro-6-methylbenzenesulfonyl)-4-methyl-3-[2-(3-quinolyl)ethynyl]benzohydrazide 
• 1361582-32-2 ethyl 2-(2-chloro-6-methylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-1-carboxylate 
• 1269500-07-3 C₂₂H₂₈ClN₃O₅S 
• 1258070-36-8 2-[[[(2-chloro-6-methyl-phenyl)sulfonyl]-methyl-amino]-methyl]-3H-benzoimidazole-4-carboxylic acid methyl ester 
• 1226949-67-2 (S)-4-(1-(3-(1-(2-chloro-6-methylphenylsulfonyl)pyrrolidin-2-yl)propylsulfonyl)piperidin-4-yloxy)pyridine 
• 1191240-21-7 (1-(2-chloro-6-methylphenylsulfonyl)piperidin-2-yl)methanol 
• 1215721-32-6 C₂₀H₂₄ClNO₃S 
• 1198055-53-6 2-chloro-6-methyl-N-{1-[(4-methylpiperidin-1-yl)carbonyl]-3-phenylpropyl}benzenesulfonamide 

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