253264-78-7Relevant academic research and scientific papers
Modulating the pH-dependent redox potential of a flavin analog via incorporation into a self-assembled monolayer on gold
Tam-Chang, Suk-Wah,Mason, James,Iverson, Isaac,Hwang, Ki-Oh,Leonard, Christa
, p. 65 - 66 (1999)
We report the first example of modifying the pH-dependent electrochemical properties of a flavin analog on gold by changing the pK(a) value of its N1 proton.
A novel fluorescent surfactant enhances the delivery of the Cas9 ribonucleoprotein and enables the identification of edited cells
Li, Jie,R?ise, Joachim Justad,Zhang, Jingtuo,Yang, Jiaying,Kerr, D. Lucas,Han, Hesong,Murthy, Niren
, p. 4562 - 4565 (2019)
In this report, we designed and synthesized a novel fluorescent single tailed surfactant (termed FEDS), which can disrupt endosomes, complex lipofectamine, and can also identify cells that have been transfected. FEDS was able to increase the gene editing
COMPOSITIONS AND METHODS FOR DELIVERY OF MACROMOLECULES
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Paragraph 00432; 00437; 00444, (2019/06/23)
The present disclosure provides endosomal disruptors, which are useful for facilitating delivery of a macromolecule to the cytoplasm of a cell. The present disclosure provides compositions comprising an endosomal disruptor and a macromolecule. The present disclosure provides methods of delivering a macromolecule to the cytoplasm of a cell.
Synthesis of symmetrical and unsymmetrical alkyl disulfides with attached flavin analog for formation of self-assembled monolayers on gold
Tam-Chang, Suk-Wah,Mason, James C.
, p. 13333 - 13344 (2007/10/03)
We describe a general procedure for the synthesis of symmetrical and unsymmetrical disulfides with an attached flavin analog. Self-assembled monolayers of these disulfides on gold have potential applications as pH sensors and electrocatalysts. The use of
