253270-13-2Relevant academic research and scientific papers
A general method for the synthesis of the N2- and N6- carcinogenic amine adducts of 2'-deoxyguanosine and 2'-deoxyadenosine
De Riccardis, Francesco,Bonala, Radha R.,Johnson, Francis
, p. 10453 - 10460 (2007/10/03)
A number of simple arylamino compounds (Figure 1) are well-established as pro-carcinogenic agents. Metabolic activation leads to a series of unstable N-hydroxy derivatives that on solvolysis, give nitrenium ions. The latter, which are regarded as the prim
