253275-89-7

Upstream product

• 253275-87-5 (1S,2S)-2-(naphthalene-2-ylsulfanyl)cyclohexanol 
• 91-60-1 2-Naphthalenethiol 
• 286-20-4 cyclohexane-1,2-epoxide 

Downstream Products

• 253275-92-2 C₁₉H₂₀O₄S 
• 253276-09-4 (+)-(4-isobutyl-phenyl)-acetic acid (1S,2S)-2-(naphthalene-2-sulfonyl)-cyclohexyl ester 
• 1146697-27-9 C₂₁H₂₂Cl₃NO₆S 
• 253276-16-3 (+)-(S)-2-(4-isobutyl-phenyl)-propionic acid (1S,2S)-2-(naphthalene-2-sulfonyl)-cyclohexyl ester 

Relevant academic research and scientific papers

A practical new chiral controller for asymmetric Diels-Alder and alkylation reactions

(formula presented) The enantiomerically pure hydroxy sulfones (+)- and (-)-2 have been prepared from 1,2-epoxycyclohexane by a simple and practical procedure. The acrylate esters of these alcohols undergo BCl3-catalyzed Diels-Alder reactions with a variety of dienes at -78 to -55°C in CH2Cl2 or C7H8 with high dienophile face selectivity (Table 1). The chiral esters so formed are readily cleaved with recovery of the controllers (+)- or (-)-2. Esters of (+)- and (-)-2 can be converted to Z-polassium enolates and alkylated with high face selectivity.