25340-80-1

Upstream product

• 75-24-1 trimethylaluminum 
• 107646-62-8 (E)-(4-bromo-but-3-en-1-yn-1-yl)trimethylsilane 
• 73395-75-2 (E)-2-(but-1-en-3-ynyl)-1,3,3-trimethylcyclohex-1-ene 

Downstream Products

• 1231960-32-9 Cy₃PAu-CC-(CH=CH)2-CC-AuPCy₃ 

Relevant academic research and scientific papers

A novel, selective, and efficient route to carotenoids and related natural products via Zr-catalyzed carboalumination and Pd- and Zn-catalyzed cross coupling.

[structure: see text]. A highly efficient and stereoselective protocol for the syntheses of symmetrical and unsymmetrical carotenoids involving Zr-catalyzed carboalumination of conjugated oligoenynes and Pd- and Zn-catalyzed alkenyl-alkenyl coupling has been developed and applied to the syntheses of beta- and gamma-carotene and vitamin A. gamma-Carotene of > or =99% isomeric purity was prepared in three linear steps (five steps overall) from beta-ionone, enyne 8, (E)-ICH=CHBr, and (E)-Me3SiC triple bond CCH=CHBr in 32% overall yield.