25344-58-5Relevant academic research and scientific papers
Synthetic and Stereochemical Studies on Phthalideisoquinoline Hemiacetals
Rozwadowska, Maria D.,Matecka, Dorota
, p. 287 - 289 (2007/10/02)
The two new phthalideisoquinoline hemiacetals rac-egenine (3) and rac-corytensine (4) are prepared by stereoselective DIBAL reduction of rac-bicuculline (1) and rac-adlumidine (2), respectively.The identity of egenine (3) with decumbensine as well as of corytensine (4) with epi-α-decumbensine and humosine A is postulated.The configuration around the anomeric center in natural (+)-egenine (3), (+)-corytensine (4) and (-)-narcotine hemiacetal (7) is deduced as (7'S), (7'R) and (7'R), respectively.
