25346-59-2

Upstream product

• 17427-08-6 trans-4-hydroxy-2-hexenal 
• 762-47-0 7-methyl-6-octen-3-one 
• 70234-77-4 bishomofarnesene 
• 127941-96-2 homofarnesene (II) 

Downstream Products

• 3208-16-0 2-ethylfuran 
• 23048-13-7 2,4-dimethyl-2-cyclopenten-1-one 
• 931-22-6 3,5-dimethyl-2-cyclopenten-1-one 
• 68014-42-6 2-benzyl-3-methoxycarbonyl-1,2,3,4-tetrahydro-9-methyl-pyrido-<3,4b>indole-1-(3-pentanone) 
• 1062575-59-0 (Z)-1-(4-methoxy-phenyl)-3-(4-oxohexylidene)-piperidin-2-one 
• 1062575-57-8 (E)-1-(4-methoxy-phenyl)-3-(4-oxohexylidene)-piperidin-2-one 
• 141804-37-7 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole 
• 141764-08-1 2-[(2R,5R)-5-Ethyl-1-((R)-1-phenyl-ethyl)-pyrrolidin-2-yl]-ethanol 
• 141764-08-1 2-[(2S,5R)-5-Ethyl-1-((R)-1-phenyl-ethyl)-pyrrolidin-2-yl]-ethanol 
• 141764-07-0 [5-Ethyl-1-((S)-1-phenyl-ethyl)-pyrrolidin-2-yl]-acetic acid methyl ester 

Relevant academic research and scientific papers

A new route to trans 2,5-dialkylpyrrolidines

Benzylic amines 8 react with ketoenoates 7 yielding, after reduction of the primary adducts, 2,5-dialkylpyrrolidines 9 (trans isomer predominating). This reaction has been applied to the synthesis of trans 2-heptyl-5-ethylpyrrolidine, a component of the venom of fire ant (Solenopsis punctaticeps).

Synthesis of 2-Alkyl-2-cyclopenten-1-ones. A Versatile Kinetic Alkylation-Ozonolysis Procedure for the Preparation of γ-Ketoaldehydes

A range of 2-alkyl-2-cyclopenten-1-ones including the prostaglandin precursor 2-(6-methoxycarbonylhexyl)-2-cyclopenten-1-one and the jasmonoid precursor 2--2-cyclopenten-1-one, have been prepared by a short synthetic route which begins with 6-methyl-5-hepten-2-one and generates the key 1,4-ketoaldehyde intermediates by a kinetic alkylation-ozonolysis procedure.

Reaction Gas Chromatography without Solvent for Identification of Nanogram Quantities of Natural Products

A method is described for trapping nanogram quantities of compounds or mixtures from a gas chromatography column with approximately 85percent efficiency and reinjecting the sample on the same or different column, with or without carrying out a reaction, and all without contamination with solvent.The method includes a solvent-free ozonolysis technique for determining the position of double bonds in alkenes by using 200 ng of sample, even when low molecular weight carbonyl compounds are produced.Characterization of carbonyl compounds by sodium borohydride reduction, hydrogenation of alkenes, and cleavage of epoxides by periodic acid at this scale, without the use of solvents, are also described.