25347-40-4

Basic information

• Product Name: Benzene, 1,1'-(2,3-dimethyl-1,4-butanediyl)bis-
• CAS NO: 25347-40-4
• Molecular Formula: C18H22
• Molecular Weight: 238.373
• Mol File: 25347-40-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(2,3-dimethyl-1,4-butanediyl)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(2,3-dimethyl-1,4-butanediyl)bis-(25347-40-4)
• EPA Substance Registry System: Benzene, 1,1'-(2,3-dimethyl-1,4-butanediyl)bis-(25347-40-4)

Safety Data

• Hazardous Substances Data: 25347-40-4(Hazardous Substances Data)

Upstream product

• 38023-36-8 1,4-diphenyl-2,3-dimethylbutadiene-1,3 
• 2114-39-8 (2-bromopropyl)-benzene 
• 74714-05-9 3,4-dibenzylthiophene 
• 74707-05-4 2,5-dibromo-3,4-dimethylthiophene 
• 300-57-2 allylbenzene 
• 31731-87-0 1-methyl-2-phenylethylmagnesium bromide 
• 626-87-9 1,4-dibromopentane 
• 6940-78-9 4-chlorobutyl bromide 
• 71-43-2 benzene 
• 2327-99-3 1-phenylpropadiene 
• 62640-71-5 2,3-dimethyl-1,4-diphenylbutane-2,3-diol 
• 6921-34-2 benzylmagnesium chloride 
• 873-49-4 cyclopropylbenzene 
• 637-50-3 1-phenylpropene 

Relevant articles and documents

Copper-catalyzed cross-coupling of functionalized alkyl halides and tosylates with secondary and tertiary alkyl Grignard reagents

Added value: A copper-based method is highly efficient for the cross-coupling of alkyl electrophiles with secondary and tertiary alkyl Grignard reagents. The method is distinguished by its broad substrate scope and high functional group tolerance. Copyright

Design and Development of New Chemical Reactions via Low-valent Titanium-induced Cleavage of Carbon - Heteroatom Bonds

Low-valent titanium (LVT)-induced regioselective cleavage of N-arylmethyl bonds in preference to N-alkyl/aryl counterparts in N-arylmethylamines has been examined in detail and culminated in the design and development of new reactions, viz. novel approach to deprotection of N-benzylamines, reductive deoxygenation of carbonyls to methylenes and reductive amination of carbonyls under neutral conditions - all involving a known bonding change, viz. the directed cleavage of C-N bonds via LVT-mediated reactions.

Syntheses of (+/-)-Deoxyschizandrin and the Lignan, 1,4-Bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane

(+/-)-Deoxyschizandrin (1) has been synthesised through a dimerisation reaction as a key step.The Grignard reagent from 1-(3,4,5-trimethoxyphenyl)-2-bromopropane (10) on reaction with 2-t-butyl-3-phenyloxaziridine gives 1,4-bis(3,4,5-trimethoxyphenyl)-2,3-dimethylbutane (11), which is cyclised using vanadium oxytrifluoride to get deoxyschizandrin (1).Following the above methodology, 1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane (2), a lignan has also been prepared.