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Usage

Uses

Used in Dye Production:
4-(propane-2-sulfonyl)aniline is used as a chemical intermediate for the synthesis of dyes, contributing to the creation of a range of colorants used in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 4-(propane-2-sulfonyl)aniline is utilized as a building block in the development of new drugs, potentially leading to advancements in medicinal chemistry.
Used in Agrochemicals:
4-(propane-2-sulfonyl)aniline is employed as a precursor in the formulation of agrochemicals, playing a part in the production of compounds that can enhance crop protection and yield.

Upstream product

• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 710-24-7 4-acetamidobenzenesulfinic acid 
• 7205-63-2 1-(1-methylethylthio)-4-nitrobenzene 
• 86810-72-2 N-(4-(isopropylsulfonyl)phenyl)acetamide 

Downstream Products

• 1054579-41-7 6-(4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-N-(4-(isopropylsulfonyl)phenyl)-5-nitropyrimidin-4-amine 
• 1224162-18-8 [4-((1R,2R)-2-benzyloxy-1-methylpropoxy)-5-trifluoromethylpyrimidin-2-yl][4-(propane-2-sulphonyl)phenyl]amine 

Relevant academic research and scientific papers

(R)-3-(N,N-DIMETHYLAMINO)PYRROLIDINE DERIVATIVES

(R)-3-(N,N-Dimethyiamino)pyrrolidine derivatives of formula (I), wherein the meaning for Cy1 is as disclosed in the description. These compounds are useful as JAK3 kinase inhibitors

Thiazolopyrimidine modulators of TRPV1

Certain TRPV1-modulating thiazolopyrimidine compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPV1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease.

Syntheses of Some Alkyl-, Cycloalkyl-, and Aryl-(4-aminophenyl)-sulfones

Syntheses of (4-aminophenyl)-alkyl, -cycloalkyl and -aryl sulfones 2 were achieved both by alkylation of 4-(acetylamino)-benzenesulfinic acid (7) to the corresponding acetanilides 9 followed by hydrolysis and by oxidation of the appropriate (4-nitrophenyl)-sulfides 11 to (4-nitrophenyl)-sulfones 1 with subsequent Bechamp reduction.