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N-(1-{(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-[(R)-1-(2-nitro-phenyl)-ethoxymethoxy]-tetrahydro-furan-2-yl}-2-oxo-1,2-dihydro-pyrimidin-4-yl)-acetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

253586-24-2

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253586-24-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 253586-24-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,5,8 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 253586-24:
(8*2)+(7*5)+(6*3)+(5*5)+(4*8)+(3*6)+(2*2)+(1*4)=152
152 % 10 = 2
So 253586-24-2 is a valid CAS Registry Number.

253586-24-2Downstream Products

253586-24-2Relevant academic research and scientific papers

Fast and reliable automated synthesis of RNA and partially 2'-O- protected precursors ('caged RNA') based on two navel, orthogonal 2'-O- protecting groups. Preliminary communication

Pitsch, Stefan,Weiss, Patrick A.,Wu, Xiaolin,Ackermann, Damian,Honegger, Thomas

, p. 1753 - 1761 (2007/10/03)

Two sets of RNA phosphoramidites, carrying the (fluoride-labile) 2'-O- [(triisopropylsilyl)oxy]methyl (=tom) group and the (photolabile) [(R)-1-(2- nitrophenyl)ethoxy]methyl (= (R)-npeom) group, were prepared (see 1-4 and 5- 8, resp.). The two protecting groups were completely orthogonal to each other. Three ribozyme-substrate constructs, protected each by a (R)-npeom group, were synthesized; on photolysis, efficient cleavage of this remaining protecting group occurred (Scheme 3). It could be demonstrated that the presence of one (R)-npeom group within a RNA strand has only a minor influence on the pairing properties of corresponding duplexes.

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