253594-55-7

Basic information

• Product Name: C₂₂H₂₇ClN₂O₂S
• Synonyms: C₂₂H₂₇ClN₂O₂S
• CAS NO: 253594-55-7
• Molecular Weight: 418.988
• Mol File: 253594-55-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₇ClN₂O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₇ClN₂O₂S(253594-55-7)
• EPA Substance Registry System: C₂₂H₂₇ClN₂O₂S(253594-55-7)

Safety Data

• Hazardous Substances Data: 253594-55-7(Hazardous Substances Data)

Upstream product

• 2037-31-2 3-chlorophenylthiol 
• 253594-54-6 4-[(5-bromo-2-pyridinyl)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester 

Downstream Products

• 253594-56-8 C₂₂H₂₇ClN₂O₄S 
• 253594-58-0 C₂₂H₂₇ClN₂O₅S 

Relevant articles and documents

MUSCARINIC ANTAGONISTS

Amide derivatives of 1,4 di-substituted piperidine compounds of formula (I) or a pharmaceutically acceptable salt, ester or solvate thereof, wherein Q and Q are each -CH=, or one of Q and Q is -CH= and the other is -N=; X is -CH2- or (a); Y and Z are -C(R)=, or one of Y and Z is -C(R)= and the other is -N=; R is 1 to 3 substituents selected from H, halogen and alkoxy; R and R are 1 to 3 substituents selected from H, halogen, alkyl and alkoxy; and R and R are H or (C1-C6) alkyl are muscarinic antagonists usuful for treating cognitive disorders such as Alzheimer's disease. Pharmaceutical compositions and methods of preparation are also disclosed.