253598-47-9Relevant academic research and scientific papers
Resolution of a CPzI precursor, synthesis and biological evaluation of (+) and (-)-N-Boc-CPzI: A further validation of the relationship between chemical solvolytic stability and cytotoxicity
Baraldi, Pier Giovanni,Cacciari, Barbara,Romagnoli, Romeo,Spalluto, Giampiero,Boyce, Christopher W.,Boger, Dale L.
, p. 3087 - 3092 (2007/10/03)
The chemical resolution, using N-tosyl-L-proline as a chiral auxiliary, of a racemate of the pyrazole analog (±)-N-Boc-CPzI of the left hand segment (CPI) of the antitumor agent CC-1065, and the cytotoxic evaluation of both enantiomers are described. The
