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3',5'-Dibromofolic acid is a synthetically modified derivative of folic acid, a water-soluble B-vitamin essential for various biological processes. 3',5'-dibromofolic acid features two bromine atoms attached at the 3' and 5' positions, which distinguishes it from the naturally occurring folic acid. The presence of bromine atoms allows for the incorporation of stable isotopes, such as deuterium (2H), for advanced analytical techniques and in vivo studies.

2536-53-0

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2536-53-0 Usage

Uses

Used in Pharmaceutical Research:
3',5'-Dibromofolic acid is utilized as a modified preparation for folic acid labeled with 2H at the 3',5'-positions. This modification is crucial for in vivo studies of folate absorption, metabolism, and turnover. By using this labeled compound, researchers can gain a deeper understanding of the mechanisms and pathways involved in folate transport and metabolism, which can contribute to the development of targeted therapies and diagnostic tools for various diseases related to folate metabolism.
Used in Biochemical Analysis:
The incorporation of stable isotopes in 3',5'-dibromofolic acid allows for the use of advanced analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. These methods can provide detailed information on the molecular structure, interactions, and dynamics of folate and its derivatives, which can be valuable for elucidating the biochemical processes and potential therapeutic targets in folate-related diseases.
Used in Drug Development:
Understanding the absorption, metabolism, and turnover of folate is essential for the development of drugs targeting folate-dependent pathways. The use of 3',5'-dibromofolic acid in in vivo studies can provide valuable insights into the pharmacokinetics and pharmacodynamics of folate analogs, which can guide the design and optimization of novel therapeutic agents for diseases such as cancer, anemia, and neurological disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 2536-53-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,3 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2536-53:
(6*2)+(5*5)+(4*3)+(3*6)+(2*5)+(1*3)=80
80 % 10 = 0
So 2536-53-0 is a valid CAS Registry Number.

2536-53-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]-3,5-dibromobenzoyl]amino]pentanedioic acid

1.2 Other means of identification

Product number -
Other names N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}-3,5-dibromophenyl)carbonyl]glutamic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2536-53-0 SDS

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