253602-55-0

Upstream product

• 7230-41-3 N-(2-fluorophenyl)-4-methylbenzenesulfonamide 
• 122-60-1 Phenyl glycidyl ether 
• 253602-53-8 N-(2-Fluorophenyl)-N-(2-hydroxy-3-phenoxypropyl)toluene-p-sulfonamide 

Relevant academic research and scientific papers

Synthesis of 2-Substituted 3,4-Dihydro-2H-1,4-benzoxazines in Water under Phase Transfer Catalysis Conditions

2-Substituted 3,4-dihydro-2H-1,4-benzoxazines have been prepared in excellent yields and short reaction times through the cyclization of hydroxysulfonamides in water under PTC conditions.

Novel concise synthesis of 2-substituted 3,4-dihydro-2H-1,4-benzoxazines by ring opening of glycidols under solid-liquid phase transfer catalysis conditions

The ring opening of glycidols with N-(2-fluorophenyl)toluene-p-sulfonamide under SL-PTC conditions, followed by ring closure with Bu(t)OK, provides a novel high yielding synthesis of 2-substituted 3,4-dihydro-2H-1,4-benzoxazines.