253603-61-1 Usage
General Description
2-(Pyrrolidin-3-yloxy)-pyridine is a chemical compound with the molecular formula C11H14N2O. It is a pyridine derivative that contains a pyrrolidin-3-yloxy group. 2-(Pyrrolidin-3-yloxy)-pyridine is often used as a precursor or intermediate in the synthesis of pharmaceutical compounds and agrochemicals. It has also been studied for its potential biological activities, including as a potential insect repellent and in the treatment of various medical conditions. 2-(Pyrrolidin-3-yloxy)-pyridine is classified as an organic compound and is important in the field of medicinal and synthetic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 253603-61-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,6,0 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 253603-61:
(8*2)+(7*5)+(6*3)+(5*6)+(4*0)+(3*3)+(2*6)+(1*1)=121
121 % 10 = 1
So 253603-61-1 is a valid CAS Registry Number.
253603-61-1Relevant articles and documents
From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors
Liang, Jun,Labadie, Sharada,Zhang, Birong,Ortwine, Daniel F.,Patel, Snahel,Vinogradova, Maia,Kiefer, James R.,Mauer, Till,Gehling, Victor S.,Harmange, Jean-Christophe,Cummings, Richard,Lai, Tommy,Liao, Jiangpeng,Zheng, Xiaoping,Liu, Yichin,Gustafson, Amy,Van der Porten, Erica,Mao, Weifeng,Liederer, Bianca M.,Deshmukh, Gauri,An, Le,Ran, Yingqing,Classon, Marie,Trojer, Patrick,Dragovich, Peter S.,Murray, Lesley
supporting information, p. 2974 - 2981 (2017/05/31)
A high-throughput screening (HTS) of the Genentech/Roche library identified a novel, uncharged scaffold as a KDM5A inhibitor. Lacking insight into the binding mode, initial attempts to improve inhibitor potency failed to improve potency, and synthesis of
