253684-34-3

Basic information

• Product Name: 1-((Z)-2-Bromo-2-phenyl-vinyl)-2-nitro-benzene
• Synonyms: 1-((Z)-2-Bromo-2-phenyl-vinyl)-2-nitro-benzene
• CAS NO: 253684-34-3
• Molecular Weight: 304.143
• Mol File: 253684-34-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-((Z)-2-Bromo-2-phenyl-vinyl)-2-nitro-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((Z)-2-Bromo-2-phenyl-vinyl)-2-nitro-benzene(253684-34-3)
• EPA Substance Registry System: 1-((Z)-2-Bromo-2-phenyl-vinyl)-2-nitro-benzene(253684-34-3)

Safety Data

• Hazardous Substances Data: 253684-34-3(Hazardous Substances Data)

Upstream product

• 253684-24-1 1-(2,2-dibromovinyl)-2-nitrobenzene 
• 98-80-6 phenylboronic acid 
• 552-89-6 2-nitro-benzaldehyde 
• 934-56-5 trimethyl(phenyl)stannane 

Relevant articles and documents

A highly selective tandem cross-coupling of gem-dihaloolefins for a modular, efficient synthesis of highly functionalized indoles

(Chemical Equation Presented) A highly efficient method of indole synthesis using gem-dihalovinylaniline substrates and an organoboron reagent was developed via a Pd-catalyzed tandem intramolecular amination and an intermolecular Suzuki coupling. Aryl, alkenyl, and alkyl boron reagents are all successfully employed, making for a versatile modular approach. The reaction tolerates a variety of substitution patterns on the aniline leading to indoles with group at C2-C7. The orthogonal approach of the sequential copper- and palladium-mediated synthesis of 1,2-diarylindoles exploited the wide availability of diverse organoboron reagents.