8-Nitroquinolin-3-ol, also known as nitroxoline, is a quinoline antimicrobial agent that is a yellow, crystalline powder. It has been used as an antibacterial and antifungal agent in pharmaceuticals, exhibiting broad-spectrum activity against both Gram-positive and Gram-negative bacteria, as well as some fungi. Its mechanism of action includes the inhibition of nucleic acid synthesis and disruption of bacterial cell membrane integrity.
25369-37-3
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Basic information
- Product Name: 8-nitroquinolin-3-ol
- Synonyms: 8-nitroquinolin-3-ol;8-Nitro-3-quinolinol
- CAS NO:25369-37-3
- Molecular Formula: C9H6N2O3
- Molecular Weight: 190.15554
- EINECS: N/A
- Product Categories: N/A
- Mol File: 25369-37-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 400.9±30.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.496±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 7.21±0.40(Predicted)
- CAS DataBase Reference: 8-nitroquinolin-3-ol(CAS DataBase Reference)
- NIST Chemistry Reference: 8-nitroquinolin-3-ol(25369-37-3)
- EPA Substance Registry System: 8-nitroquinolin-3-ol(25369-37-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 25369-37-3(Hazardous Substances Data)
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25369-37-3 Usage
Uses
Used in Pharmaceutical Industry:8-Nitroquinolin-3-ol is used as an antibacterial and antifungal agent for the treatment of urinary tract infections and various bacterial and fungal infections. It is effective in both preventing and treating infections due to its broad-spectrum activity and ability to inhibit nucleic acid synthesis and disrupt bacterial cell membrane integrity.
Check Digit Verification of cas no
The CAS Registry Mumber 25369-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,3,6 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.Calculate Digit Verification of CAS Registry Number 25369-37:
(7*2)+(6*5)+(5*3)+(4*6)+(3*9)+(2*3)+(1*7)=123
123 % 10 = 3
So 25369-37-3 is a valid CAS Registry Number.
25369-37-3Upstream product
25369-37-3Downstream Products
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8-nitroquinolin-3-ol
