25369-43-1 Usage
General Description
2-Oxo-Indoline-7-Carboxylic Acid is a chemical compound known to be a component in the synthesis of various pharmaceutical drugs and substances. It is characterized by the presence of a carboxylic acid group and an oxo group attached to an indoline scaffold. As an intermediate, it plays a crucial role in organic synthesis due to the broad applicability of its indoline core in medicinal chemistry. Indoline derivatives such as this are a significant class of heterocyclic compounds, appearing in many naturally occurring alkaloids and bioactive small molecules, thereby highlighting their importance in drug discovery and development. Its precise role and behavior in reactions depend on its surroundings and other reaction conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 25369-43-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,3,6 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 25369-43:
(7*2)+(6*5)+(5*3)+(4*6)+(3*9)+(2*4)+(1*3)=121
121 % 10 = 1
So 25369-43-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO3/c11-7-4-5-2-1-3-6(9(12)13)8(5)10-7/h1-3H,4H2,(H,10,11)(H,12,13)
25369-43-1Relevant articles and documents
Rational design, synthesis, and structure-activity relationship of benzoxazolones: New potent mglu5 receptor antagonists based on the fenobam structure
Ceccarelli, Simona M.,Jaeschke, Georg,Buettelmann, Bernd,Huwyler, Joerg,Kolczewski, Sabine,Peters, Jens-Uwe,Prinssen, Eric,Porter, Richard,Spooren, Will,Vieira, Eric
, p. 1302 - 1306 (2008/09/20)
A novel class of potent and stable mGlu5 receptor antagonists was developed by combining information from a high-throughput screening campaign with the structure of the known anxiolytic fenobam. Representative compounds from this class show favorable phar
