25370-97-2

Basic information

• Product Name: O-(p-toluenesulfonyl)-N-methylhydroxylamine
• Synonyms: O-(p-toluenesulfonyl)-N-methylhydroxylamine
• CAS NO: 25370-97-2
• Molecular Weight: 201.246
• Mol File: 25370-97-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 49-52 °C
• Boiling Point: 297.0±33.0 °C(Predicted)
• Density: 1.237±0.06 g/cm3(Predicted)
• CAS DataBase Reference: O-(p-toluenesulfonyl)-N-methylhydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: O-(p-toluenesulfonyl)-N-methylhydroxylamine(25370-97-2)
• EPA Substance Registry System: O-(p-toluenesulfonyl)-N-methylhydroxylamine(25370-97-2)

Safety Data

• Hazardous Substances Data: 25370-97-2(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 25370-96-1 O-(p-toluenesulfonyl)-N-tert-butoxycarbonyl-N-methylhydroxylamine 

Downstream Products

• 82820-63-1 Toluene-4-sulfonate5-methoxycarbonyl-1-methyl-1-methylamino-1,2,3,6-tetrahydro-pyridinium; 
• 81375-36-2 Toluene-4-sulfonate2-methyl-2-methylamino-2,3,4,9-tetrahydro-1H-β-carbolin-2-ium; 
• 81375-25-9 Toluene-4-sulfonate8-bromo-2-methyl-2-methylamino-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium; 
• 82820-55-1 Toluene-4-sulfonateN,N,N-tributyl-N'-methyl-hydrazinium; 
• 82820-57-3 Toluene-4-sulfonateN-dodecyl-N,N,N'-trimethyl-hydrazinium; 
• 110-68-9 N-n-butyl-N-methylamine 
• 82820-61-9 Toluene-4-sulfonateN,N,N'-trimethyl-N-phenyl-hydrazinium; 

Relevant articles and documents

Intramolecular N-Me and N-H aminoetherification for the synthesis ofN-unprotected 3-amino-O-heterocycles

A mild Rh-catalyzed method for synthesis of cyclic unprotected N-Me and N-H 2,3-aminoethers using an olefin aziridination-aziridine ring-opening domino reaction has been developed. The method is readily applicable to the stereocontrolled synthesis of a va

O-Arenesulfonyl-N-alkylhydroxylamines as Aminating Reagents

O-(p-Toluenesulfonyl)-N-methyl-, -N-ethyl-, and -N-isopropil-hydroxylamines and O-mesitylenesulfonyl-N-methylhydroxylamine were prepared.The N-methyl and N-ethyl derivatives were found to react with tertiary amines and triphenylphosphine to give the corresponding N-(alkylamino)ammonium salts and P-(alkylamino)phosphonium salts, but the N-isopropyl derivative was less reactive, probably due to steric effects.These reagents also reacted with tri-n-butylborane to give the corresponding alkyl-n-butylamines.Keywords-- electrophilic aminating reagent; tert-butoxycarbonylation; di-tert-butyl dicarbonate; N-(methylamino)ammonium salts; P-(methylamino)triphenylphosphonium salt; N-(methylamino)pyridinium salt; secondary amines