25370-97-2

Upstream product

• 25370-96-1 O-(p-toluenesulfonyl)-N-tert-butoxycarbonyl-N-methylhydroxylamine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 82820-63-1 Toluene-4-sulfonate5-methoxycarbonyl-1-methyl-1-methylamino-1,2,3,6-tetrahydro-pyridinium; 
• 81375-36-2 Toluene-4-sulfonate2-methyl-2-methylamino-2,3,4,9-tetrahydro-1H-β-carbolin-2-ium; 
• 81375-25-9 Toluene-4-sulfonate8-bromo-2-methyl-2-methylamino-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium; 
• 82820-57-3 Toluene-4-sulfonateN-dodecyl-N,N,N'-trimethyl-hydrazinium; 
• 110-68-9 N-n-butyl-N-methylamine 
• 82820-59-5 Toluene-4-sulfonateN-cyclohexyl-N,N,N'-trimethyl-hydrazinium; 
• 82820-61-9 Toluene-4-sulfonateN,N,N'-trimethyl-N-phenyl-hydrazinium; 
• 81375-21-5 Toluene-4-sulfonate2,8-dimethyl-2-methylamino-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium; 
• 81375-23-7 Toluene-4-sulfonate8-chloro-2-methyl-2-methylamino-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium; 
• 437608-06-5 4-tert-butyl-2-tosyloxycyclohexanone 
• 146040-84-8 α-tosyloxycycloheptanone 
• 81447-33-8 toluene-4-sulfonic acid 1-methyl-2-oxobutyl ester 
• 80520-05-4 2-oxoheptyl 4-methylbenzenesulfonate 
• 81447-32-7 toluene-4-sulfonic acid 1-methyl-2-oxo-propyl ester 

Relevant academic research and scientific papers

Intramolecular N-Me and N-H aminoetherification for the synthesis ofN-unprotected 3-amino-O-heterocycles

A mild Rh-catalyzed method for synthesis of cyclic unprotected N-Me and N-H 2,3-aminoethers using an olefin aziridination-aziridine ring-opening domino reaction has been developed. The method is readily applicable to the stereocontrolled synthesis of a va

Direct α-oxytosylation of carbonyl compounds: One-pot synthesis of heterocycles

N-Methyl-O-tosylhydroxylamine is an effective reagent for the direct α-oxytosylation of carbonyl compounds. The reactions proceed smoothly at room temperature in the presence of both moisture and air and functional group tolerance in the substrate is good. With nonsymmetrical substrates regioselectivity for primary over secondary centers is observed and complete regiospecificity for primary over tertiary centers is obtained. Addition of a bis-heteronucleophile directly to the crude reaction mixture in a one-pot process leads to the corresponding heterocyclic product.

O-Arenesulfonyl-N-alkylhydroxylamines as Aminating Reagents

O-(p-Toluenesulfonyl)-N-methyl-, -N-ethyl-, and -N-isopropil-hydroxylamines and O-mesitylenesulfonyl-N-methylhydroxylamine were prepared.The N-methyl and N-ethyl derivatives were found to react with tertiary amines and triphenylphosphine to give the corresponding N-(alkylamino)ammonium salts and P-(alkylamino)phosphonium salts, but the N-isopropyl derivative was less reactive, probably due to steric effects.These reagents also reacted with tri-n-butylborane to give the corresponding alkyl-n-butylamines.Keywords-- electrophilic aminating reagent; tert-butoxycarbonylation; di-tert-butyl dicarbonate; N-(methylamino)ammonium salts; P-(methylamino)triphenylphosphonium salt; N-(methylamino)pyridinium salt; secondary amines