25372-07-0

Basic information

• Product Name: 1-(4-imidazol-1-ylphenyl)imidazole
• Synonyms: 1-(4-imidazol-1-ylphenyl)imidazole;1,1'-(1,4-phenylene)bis-1H-Imidazole
• CAS NO: 25372-07-0
• Molecular Formula: C₁₂H₁₀N₄
• Molecular Weight: 210.2346
• Mol File: 25372-07-0.mol
• Article Data: 20

Chemical Properties

• Melting Point: 216-217 °C
• Boiling Point: 419.4°Cat760mmHg
• Flash Point: 207.5°C
• Appearance: /
• Density: 1.22g/cm³
• PKA: 5.53±0.10(Predicted)
• CAS DataBase Reference: 1-(4-imidazol-1-ylphenyl)imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-imidazol-1-ylphenyl)imidazole(25372-07-0)
• EPA Substance Registry System: 1-(4-imidazol-1-ylphenyl)imidazole(25372-07-0)

Safety Data

• Hazardous Substances Data: 25372-07-0(Hazardous Substances Data)

Usage

General Description

1-(4-imidazol-1-ylphenyl)imidazole is a chemical compound with the molecular formula C11H10N4. It is an imidazole derivative with a phenyl group and an imidazolyl group. 1-(4-imidazol-1-ylphenyl)imidazole is commonly used as an antifungal agent and has been studied for its potential applications in the treatment of various fungal infections. It works by inhibiting the growth of fungi and disrupting their cell membranes, making it effective in the treatment of conditions such as athlete's foot and ringworm. Additionally, 1-(4-imidazol-1-ylphenyl)imidazole has also been investigated for its potential anti-inflammatory and anti-cancer properties, making it a versatile compound with a range of potential therapeutic uses.

Upstream product

• 288-32-4 1H-imidazole 
• 106-39-8 bromochlorobenzene 
• 106-37-6 1.4-dibromobenzene 
• 624-38-4 para-diiodobenzene 

Downstream Products

• 1360459-88-6 [Zn(II)(1,4-bis(1-imidazolyl)-benzene)(pimelate)]*H₂O 
• 1360459-86-4 [Co(II)(1,4-bis(1-imidazolyl)-benzene)(pimelate)] 
• 1360459-87-5 [Cd(II)(1,4-bis(1-imidazolyl)-benzene)(pimelate)] 

Relevant articles and documents

Polynuclear architectures with di- and tricarbene ligands

The 1,3,5-triimidazolium-substituted benzene cation in H 3-1(PF6)3 reacts with Hg(OAc)2 to yield the cylinder-like trinuclear hexacarbene complex [Hg3(1) 2](PF6)6. Rea

(CC*) Cyclometalated binuclear N-heterocyclic biscarbene platinum(ii) complexes-highly emissive phosphorescent emitters

A series of bimetallic N-heterocyclic carbene (NHC) platinum(ii) complexes with the general formula [Pt(NHC)(L)]2Ph were synthesized, which are composed of two [Pt(NHC)(L)] (L = acetylacetone, dipivaloylmethane or dimesitoylmethane; NHC = 3-met

Tuning Gate-Opening of a Flexible Metal–Organic Framework for Ternary Gas Sieving Separation

In comparison with the fast development of binary mixture separations, ternary mixture separations are significantly more difficult and have rarely been realized by a single material. Herein, a new strategy of tuning the gate-opening pressure of flexible

Nucleation of Tiny Silver Nanoparticles by Using a Tetrafacial Organic Molecular Barrel: Potential Use in Visible-Light-Triggered Photocatalysis

Coordination-driven self-assembly of discrete molecular architectures of diverse shapes and sizes has been well studied in the last three decades. Use of dynamic imine bonds for designing analogous metal-free architectures has become a growing challenge r

Function-oriented ionic polymers having high-density active sites for sustainable carbon dioxide conversion

On the basis of the development of function-oriented synthesis (FOS), we presented for the first time an efficient and one-pot construction of functional ionic polymers (FIPs) through the phenol-formaldehyde condensation process (pre-synthetic approach); FIPs had high density of Br?nsted acidic and ionic sites. Considering the electrophilic-nucleophilic dual activation of phenolic hydroxyl groups and bromide anions, the imidazolium-based FIP-Im exhibited high activity for metal-, solvent- and additive-free synthesis of cyclic carbonates from CO2 and epoxides under mild conditions. Then, to obtain higher ionic density and a more flexible skeleton, FIP-Im@QA was also prepared by implanting quaternary ammonium (QA) in the framework of FIP-IMvia the Williamson ether synthesis (post-synthetic modification), which demonstrated high efficiency in the N-formylation reaction of multitudinous secondary amines with CO2 and PhSiH3 at ambient temperature. More interestingly, these function-oriented catalysts were compatible with the target transformation under low CO2 concentration (15% in 85% N2, v/v) and were also reused for more than six times without a significant loss of activity and selectivity. Therefore, this study could not only facilitate the design and construction of FIPs, but also provide sustainable protocols for efficient production of value-added chemicals from CO2 under mild conditions.