25372-09-2

Basic information

• Product Name: 1-(2,6-dimethylphenyl)-1H-imidazole
• Synonyms: 1-(2,6-dimethylphenyl)-1H-imidazole
• CAS NO: 25372-09-2
• Molecular Weight: 172.23
• Mol File: 25372-09-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(2,6-dimethylphenyl)-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-dimethylphenyl)-1H-imidazole(25372-09-2)
• EPA Substance Registry System: 1-(2,6-dimethylphenyl)-1H-imidazole(25372-09-2)

Safety Data

• Hazardous Substances Data: 25372-09-2(Hazardous Substances Data)

Usage

General Description

1-(2,6-dimethylphenyl)-1H-imidazole, also known as 2,6-dimethylphenylimidazole, is a chemical compound with the molecular formula C11H12N2. It is a derivative of imidazole and belongs to the class of organic compounds known as phenylimidazoles. This chemical is commonly used in the pharmaceutical industry for its potential as an antifungal agent, as it has been shown to inhibit the growth of certain fungi. 1-(2,6-dimethylphenyl)-1H-imidazole is also used in research and development for its ability to act as a ligand in coordination chemistry, forming coordination complexes with transition metals. Additionally, it has been studied for its potential use as a corrosion inhibitor in industrial applications.

Upstream product

• 50-00-0 formaldehyd 
• 131543-46-9 Glyoxal 
• 87-62-7 2,6-dimethylaniline 
• 288-32-4 1H-imidazole 
• 576-22-7 2-Bromo-m-xylene 
• 12775-96-1 copper 
• 576-26-1 2.6-dimethylphenol 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 1385782-69-3 3-[3,28-diacetoxylup-20⁽²⁹⁾-en-30-yl]-1-(2,6-dimethylphenyl)-1H-imidazol-3-ium bromide 
• 1448545-87-6 C₂₃H₂₅FeN₂⁽¹⁺⁾*Cl^(1-) 
• 1355955-84-8 1-(2,6-dimethylphenyl)-3-[((4bS,8R,8aR)-2-isopropyl-8-(methoxycarbonyl)-4b,8-dimethyl-4b,5,6,7,8,8a,9,10-octahydrophenanthren-3-yl)methyl]-3H-imidazol-1-ium chloride 

Relevant articles and documents

High-yield synthesis of novel imidazoles and triazoles from alcohols and phenols

A variety of alcohols and phenols are converted into their corresponding imidazoles and triazoles in high yields by a facile reaction with N,N1-carbonyldiimidazole (CDI) or N,N1-carbonylditriazole (CDT) in acetonitrile. The reactions of allylic alcohols, enols and phenols with CDI or CDT are unprecedented. Evidence is provided which suggests that the reaction with alcohols proceeds via the corresponding carbamates by an S(N)i mechanism.

One pot tandem dual CC and CO bond reductions in the β-alkylation of secondary alcohols with primary alcohols by ruthenium complexes of amido and picolyl functionalized N-heterocyclic carbenes

Two different classes of ruthenium complexes, namely, [1-mesityl-3-(2,6-Me2-phenylacetamido)-imidazol-2-ylidene]Ru(p-cymene)Cl (1c) and {[1-(pyridin-2-ylmethyl)-3-(2,6-Me2-phenyl)-imidazol-2-ylidene]Ru(p-cymene)Cl}Cl (2c), successfully catalyzed the one-pot tandem alcohol-alcohol coupling reactions of a variety of secondary and primary alcohols, in moderate to good yields of ca. 63-89%. The mechanistic investigation performed on two representative catalytic substrates, 1-phenylethanol and benzyl alcohol using the neutral ruthenium (1c) complex showed that the catalysis proceeded via a partially reduced CC hydrogenated carbonyl species, [PhCOCH2CH2Ph] (3′), to the fully reduced CO and CC hydrogenated secondary alcohol, [PhCH(OH)CH2CH2Ph] (3). Furthermore, the time dependent study showed that the major product of the catalysis modulated between (3′) and (3) during the catalysis run performed over an extended period of 120 hours. Finally, the practical utility of the alcohol-alcohol coupling reaction was demonstrated by preparing five different flavan derivatives (13-17) related to various bioactive flavonoid natural products, in a one-pot tandem fashion.

Ion channel modulating agents

The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general Formula (I) and a pharmaceutically acceptable salt or an oxide or a hydrate