Eicosapentaenoic acid (EPA), also known as ePA or icosapentaenoic acid, is an omega-3 fatty acid with the chemical structure of a carboxylic acid featuring a 20-carbon chain and five cis double bonds. It is a polyunsaturated fatty acid (PUFA) that serves as a precursor for various eicosanoids, including prostaglandin-3, thromboxane-3, and leukotriene-5 groups. EPA is essential for human health and is commonly found in oily fish, fish oil, and certain types of seaweed, as well as in trace amounts in some plants like purslane.
25378-27-2
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Basic information
- Product Name: EPA
- Synonyms: 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID;5,8,11,14,17-EICOSAPENTAENOIC ACID;ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID;ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID;ALL CIS 5-8-11-14-17 EPA;5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID;CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID;EPA
- CAS NO:25378-27-2
- Molecular Formula: C20H30O2
- Molecular Weight: 302.45
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: −54-−53 °C(lit.)
- Boiling Point: 468.9°Cat760mmHg
- Flash Point: 355.7°C
- Appearance: /liquid
- Density: 0.943 g/mL at 25 °C(lit.)
- Vapor Pressure: 4.36E-10mmHg at 25°C
- Refractive Index: n20/D 1.4977(lit.)
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: EPA(CAS DataBase Reference)
- NIST Chemistry Reference: EPA(25378-27-2)
- EPA Substance Registry System: EPA(25378-27-2)
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Safety Data
- Hazard Codes: C
- Statements: 34
- Safety Statements: 26-36/37/39-45
- RIDADR: UN 3265 8/PG 3
- WGK Germany: 3
- RTECS:
- F: 8-10-23
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 25378-27-2(Hazardous Substances Data)
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25378-27-2 Usage
Uses
Used in Skin Care:EPA is used as an emollient and skin-conditioning agent for its ability to repair and maintain the skin barrier functions. It is said to improve the structure and function of the skin cell membrane, and may also possess anti-irritant and anti-inflammatory properties.
Used in Nutrition:
EPA is used as a dietary supplement for its role as a precursor to docosahexaenoic acid (DHA), which is important for various physiological functions. It is obtained in the human diet by consuming oily fish or fish oil, such as cod liver, herring, mackerel, salmon, menhaden, and sardine, as well as various types of edible seaweed. It is also found in human breast milk.
Used in Medical Applications:
EPA is used in medical applications to support cardiovascular health due to its role as a precursor for prostaglandin-3, which inhibits platelet aggregation. It may also have potential benefits for individuals with medical conditions like diabetes or certain allergies, as these conditions can limit the body's capacity for metabolization of EPA from alpha-linolenic acid (ALA).
Used in Pharmaceutical Industry:
Under the brand name Decabid (Lilly), EPA is used as a pharmaceutical agent for its various health benefits, including its role in maintaining skin health and supporting cardiovascular function.
Check Digit Verification of cas no
The CAS Registry Mumber 25378-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,3,7 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.Calculate Digit Verification of CAS Registry Number 25378-27:
(7*2)+(6*5)+(5*3)+(4*7)+(3*8)+(2*2)+(1*7)=122
122 % 10 = 2
So 25378-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h10-19H,2-9H2,1H3,(H,21,22)/b11-10+,13-12+,15-14+,17-16+,19-18+
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25378-27-2Downstream Products
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