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L778123 is a potent and selective antagonist of the serotonin 5-HT2A receptor, a protein found in the central nervous system. It has been studied for its potential therapeutic use in the treatment of various psychiatric and neurological disorders, including anxiety, depression, and schizophrenia. L778123 modulates serotonin receptor activity and influences neurotransmitter release, showing promising effects in preclinical trials. Its ability to block the 5-HT2A receptor may lead to the development of novel treatments for conditions associated with serotonin dysfunction, and ongoing research aims to fully elucidate its clinical potential and safety profile.

253863-00-2

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  • 4-[[5-[[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl]imidazol-1-yl]methyl]benzonitrile,hydrochloride

    Cas No: 253863-00-2

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253863-00-2 Usage

Uses

Used in Pharmaceutical Industry:
L778123 is used as a therapeutic agent for the treatment of psychiatric and neurological disorders such as anxiety, depression, and schizophrenia. Its selective antagonism of the 5-HT2A receptor modulates serotonin receptor activity and influences neurotransmitter release, potentially leading to novel treatments for conditions associated with serotonin dysfunction.
Used in Research and Development:
L778123 is used as a research tool in preclinical trials to study the effects of 5-HT2A receptor antagonism on various psychiatric and neurological disorders. Its ability to modulate serotonin receptor activity and influence neurotransmitter release provides valuable insights into the development of new treatments and therapeutic strategies for serotonin-related conditions.
Used in Drug Discovery and Development:
L778123 serves as a lead compound in the discovery and development of new drugs targeting the serotonin 5-HT2A receptor. Its potent and selective antagonism of the receptor offers a promising starting point for the design and optimization of novel therapeutic agents with improved efficacy, safety, and pharmacokinetic properties.

Check Digit Verification of cas no

The CAS Registry Mumber 253863-00-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,3,8,6 and 3 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 253863-00:
(8*2)+(7*5)+(6*3)+(5*8)+(4*6)+(3*3)+(2*0)+(1*0)=142
142 % 10 = 2
So 253863-00-2 is a valid CAS Registry Number.
InChI:InChI=1/C22H20ClN5O.ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;/h1-7,10,12,16H,8-9,13-15H2;1H

253863-00-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[[5-[[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl]imidazol-1-yl]methyl]benzonitrile,hydrochloride

1.2 Other means of identification

Product number -
Other names 4-[(5-{[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl}-1h-imidazol-1-yl)methyl]benzonitrile hydrochloride(1:1)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:253863-00-2 SDS

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