2543-40-0

Basic information

• Product Name: H-SER-GLY-GLY-OH
• Synonyms: L-SER-GLY-GLY;H-SER-GLY-GLY-OH;L-Ser-Gly-Gly-OH;Ser-Gly-Gly-OH≥ 99% (TLC)
• CAS NO: 2543-40-0
• Molecular Formula: C7H13N3O5
• Molecular Weight: 219.2
• Mol File: 2543-40-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 216 °C (decomp)
• Boiling Point: 750.4±60.0 °C(Predicted)
• Appearance: /
• Density: 1.440±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.29±0.10(Predicted)
• CAS DataBase Reference: H-SER-GLY-GLY-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-SER-GLY-GLY-OH(2543-40-0)
• EPA Substance Registry System: H-SER-GLY-GLY-OH(2543-40-0)

Safety Data

• Hazardous Substances Data: 2543-40-0(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Relevant articles and documents

THERAPEUTIC AGENT FOR PRURITUS

The present inventors isolated clone BM095 from a human antibody phage library, which had a strong growth inhibitory activity in the IL-31-dependent Ba/F3 cell growth assay system. When administered to pruritus model mice, the anti-mouse NR10 neutralizing antibody exhibited a marked symptom-suppressing effect. Thus, it was revealed that anti-NR10 neutralizing antibodies are useful as therapeutic agents for pruritus.

Pharmaceutical preparations having diuretic activity

Pharmaceutical preparations having diuretic activity and comprising a peptide of the formula STR1 wherein (a) R1 and R2 are hydrogen and R3 is --OH, or STR2 or Y, or wherein (b) R1 is hydrogen, R2 is CH2 OH or STR3 and R3 is --OH or Y, or wherein (c) R1 is --CH2 OH and R2 is hydrogen or STR4 and R3 is --OH or Y, or wherein (d) R1 is STR5 R2 is hydrogen or --CH2 OH and R3 is --OH, --NHCH2 COOH, or Y, and wherein X is hydrogen, methyl, prolyl, or an N-protective group, and Y is --NH2, --OR4, wherein R4 is linear or branched alkyl or cyclolalkyl having from 1 to 8 carbon atoms, benzyl, phenyl, or STR6