254909-18-7

Upstream product

• 103201-79-2 (3R,7aS)-3-phenyl-tetrahydro-pyrrolo[1,2-c]oxazol-5-one 
• 254909-17-6 (2R,5S,7R)-7-cyanomethyl-8-oxo-2-phenyl-1-aza-3-oxa-bicyclo[3.3.0]octane 

Downstream Products

• 864381-65-7 (2R,5S,7S)-7-(N-benzyloxycarbonyl-2-aminoethyl)-8-oxo-2-phenyl-1-aza-3-oxa-bicyclo[3.3.0]octane 
• 864381-70-4 [2-((3S,5S)-5-Hydroxymethyl-2-oxo-pyrrolidin-3-yl)-ethyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Stereoselective synthesis of conformationally constrained ω -amino acid analogues from pyroglutamic acid

Bicyclic lactams derived from pyroglutamic acid provide a useful scaffold for synthesis of conformationally restricted analogues of lysine, ornithine and glutamine, as well as an Ala-Ala dipeptide analogue. Amino alcohol and carboxylic acid derivatives ar

Novel peptidomimetic structures: Enantioselective synthesis of conformationally constrained lysine, ornithine and alanine analogues from pyroglutamic acid

Conformationally constrained lysine and ornithine analogues, and an L- Ala-L-Ala dipeptide analogue, are available from pyroglutamic acid.