254990-95-9

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 254990-84-6 (S)-2-benzyl-[N-(benzyloxycarbonyl)]propandiamine 
• 2612-30-8 2-benzyl-1,3-propanediol 
• 110270-49-0 (R)-3-acetoxy-2-benzyl-1-propanol 
• 254990-82-4 Methanesulfonic acid (R)-2-(benzyloxycarbonylamino-methyl)-3-phenyl-propyl ester 
• 158045-02-4 (R)-3-amino-2-benzylpropane 
• 254990-76-6 (R)-1-acetoxy-3-azido-2-benzylpropane 
• 173216-45-0 (R)-3-azido-2-benzylpropanol 
• 254990-81-3 (R)-2-benzyl-3-[(N-benzyloxycarbonyl)amino]-1-propanol 
• 254990-83-5 (R)-3-azido-2-benzyl-[N-(benzyloxycarbonyl)]propanamine 
• 129600-11-9 (S)-1-acetoxy-2-benzyl-3-(methanesulfonyloxy)propane 

Downstream Products

• 254990-93-7 (R)-2-benzyl-[N-(tert-butoxycarbonyl)]-1,3-propandiamine 

Relevant academic research and scientific papers

Synthesis of asymmetrized 2-benzyl-1,3-diaminopropane by a chemoenzymatic route: A tool for combinatorially developing peptidomimetics

Both enantiomers of monoacetamide 5, together with 'dipeptides' 30a,b and monocarbamates 24, (R)-43 and (S)-43, all derived from 2-benzyl-1,3- diaminopropane 4, were synthesized by a chemoenzymatic route starting from the known monoacetate 12. The behaviour of 4 and of the bis(acylated) derivatives 8-11 with respect to hydrolytic enzymes is also presented, together with an extensive study on the configurational stability of monoacylated derivatives of 4.