25501-08-0

Basic information

• Product Name: 5-Aza-2'-deoxyuridine
• Synonyms: 5-Aza-2'-deoxyuridine;5-Aza-2a€-deoxyuridine
• CAS NO: 25501-08-0
• Molecular Formula: C8H11N3O5
• Molecular Weight: 229.19004
• Product Categories: Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 25501-08-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.90±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Water (Slightly)
• PKA: 7.70±0.20(Predicted)
• CAS DataBase Reference: 5-Aza-2'-deoxyuridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Aza-2'-deoxyuridine(25501-08-0)
• EPA Substance Registry System: 5-Aza-2'-deoxyuridine(25501-08-0)

Safety Data

• Hazardous Substances Data: 25501-08-0(Hazardous Substances Data)

Usage

Description

5-Aza-2'-deoxyuridine is a nucleoside analog and a metabolite of 5-aza-2'-deoxycytidine (A796950), which is a cancer treatment agent. It plays a significant role in the field of oncology due to its ability to inhibit the growth of specific cancer cell lines.

Uses

Used in Oncology:
5-Aza-2'-deoxyuridine is used as an inhibitor for the growth of pancreatic endocrine tumor cell lines. It is particularly effective in combating pancreatic endocrine tumors by interfering with the cell's replication and division processes, thereby limiting the tumor's growth and progression.
Additionally, as a metabolite of 5-aza-2'-deoxycytidine, 5-Aza-2'-deoxyuridine may also contribute to the overall therapeutic effects of cancer treatments that utilize its parent compound, potentially enhancing the efficacy of such treatments in various cancer types.