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6-bromo-4-methyl-7-nitro-1H-benzoimidazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 255064-11-0 Structure
  • Basic information

    1. Product Name: 6-bromo-4-methyl-7-nitro-1H-benzoimidazole
    2. Synonyms: 6-bromo-4-methyl-7-nitro-1H-benzoimidazole
    3. CAS NO:255064-11-0
    4. Molecular Formula:
    5. Molecular Weight: 256.059
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 255064-11-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-bromo-4-methyl-7-nitro-1H-benzoimidazole(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-bromo-4-methyl-7-nitro-1H-benzoimidazole(255064-11-0)
    11. EPA Substance Registry System: 6-bromo-4-methyl-7-nitro-1H-benzoimidazole(255064-11-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 255064-11-0(Hazardous Substances Data)

255064-11-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 255064-11-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,5,0,6 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 255064-11:
(8*2)+(7*5)+(6*5)+(5*0)+(4*6)+(3*4)+(2*1)+(1*1)=120
120 % 10 = 0
So 255064-11-0 is a valid CAS Registry Number.

255064-11-0Relevant articles and documents

Benzimidazole derivatives. 2. Synthesis and structure-activity relationships of new azabicyclic benzimidazole-4-carboxylic acid derivatives with affinity for serotoninergic 5-HT3 receptors

López-Rodríguez, María L.,Benhamú, Bellinda,Morcillo, M. José,Tejada, Ignacio D.,Orensanz, Luis,Alfaro, M. José,Martín, M. Isabel

, p. 5020 - 5028 (1999)

A new series of azabicyclic benzimidazole-4-carboxamides 2-21 and - carboxylates 22-30 were synthesized and evaluated for binding affinity at serotoninergic 5-HT3 and 5-HT4 receptors in the CNS. Most of the synthesized compounds exhibited high or very high affinity for the 5-HT3 binding site and low to no significant affinity for the 5-HT4 receptor. SAR observations indicated that a halogen atom at the 6-position and a nitro group at the 7-position of the benzimidazole ring is the best substitution pattern for 5-HT3 affinity and 5-HT3/5-HT4 selectivity, as well as no substitution in this ring. (S)-(-)-N-(Quinuclidin-3-yl)benzimidazole-4- carboxamides 2, 8, and 14 bound at central 5-HT3 sites with high affinity (K(i) = 2.6, 0.13, and 1.7 nM, respectively) and excellent selectivity over serotonin 5-HT4 and 5-HT(1A) receptors (K(i) > 1000-10000 nM). Furthermore, these new 5-HT3 receptor ligands were pharmacologically characterized as potent and selective 5-HT3 antagonists in the isolated guinea pig ileum (pA2 = 9.6, 9.9, and 9.1, respectively).

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