255065-85-1Relevant academic research and scientific papers
Synthesis and photoisomerization of 3-cyano-6,6-dimethyl-4-(4-nitro- phenylvinyl)-5,6-dihydropyran-2-one
Jansone,Fleisher,Andreeva,Leite,Popelis,Lukevics
, p. 1584 - 1590 (2003)
The condensation of 4-nitrobenzaldehyde with 3-cyano-4,6,6-trimethyl-5,6- dihydropyran-2-one leads to the formation of a crotonization product and a compound of the Michael adduct type. The main product of the photochemical conversion of (E)-3-cyano-6,6-dimethyl-4-(4-nitrophenylvinyl)-5,6-dihydropyran- 2-one is the Z-isomer. Investigation of the photoisomerization of 3-cyano-6,6-dimethyl-4-(4-nitrophenylvinyl)-5,6-dihydropyran-2-one by the semiempirical AM1 method showed that in the ground state the E-isomer was thermodynamically more stable than the Z-isomer. E-Z-photoisomerization is effected most probably through the lowest excited singlet state S1.
Vasodilating and antiarrhythmic activity of heteryl lactones
Leite, Ludmila,Jansone, Daina,Veveris, Maris,Cirule, Helena,Popelis, Yuris,Melikyan, Gagik,Avetisyan, Anna,Lukevics, Edmunds
, p. 859 - 865 (1999)
A new series of unsaturated γ- and δ-lactones with pyridyl, quinolyl and nitrophenyl substituents (9, 10) have been synthesized by the condensation of unsaturated methyl lactones with heteryl aldehyde or nitrobenzaldehyde in the base-catalysed aldol react
Synthesis and cytotoxic activity of 4-substituted 3-cyano-6,6-dimethyl-5,6- dihydro-2-pyranones
Leite,Jansone,Fleisher,Kazhoka,Popelis,Veretennikova,Shestakova,Domracheva,Lukevics
, p. 715 - 724 (2004)
The respective 4-(arylvinyl)lactones and compounds of the Michael adduct type were synthesized by the condensation of substituted benzaldehydes with 3-cyano-4,6,6-trimethyl-5,6-dihydro-2-pyranone in the presence of catalytic amounts of sodium hydroxide. I
