255065-88-4

Upstream product

• 134-81-6 benzil 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 105-39-5 chloroacetic acid ethyl ester 
• 1728-97-8 2-(4-dimethylaminophenyl)-4,5-diphenyl-1H-imidazole 

Downstream Products

• 1272542-00-3 C₃₃H₃₁N₅O₂ 
• 1272542-01-4 2-(5-(4-(dimethylamino)phenyl)-2,4-diphenyl-1H-imidazole-1-yl)-N'-(4-hydroxyl-3-methoxybenzylidene)acetohydrazide 

Relevant academic research and scientific papers

Synthesis of imidazole derivatives: Ester and hydrazide compounds with antioxidant activity using ionic liquid as an efficient catalyst

The pyrrolidinium hydrogen sulfate (PHS) was used as an excellent ionic liquid catalyst for the preparation of many imidazoles moiety, which have biologically application via one-pot multicomponent reaction. Imidazoles were afforded through the reaction o

Substituted imidazole derivatives as novel cardiovascular agents

A series of novel substituted imidazole derivatives were synthesized and have been screened in vivo for their hypotensive and acute toxicity activities. Out of seventeen compounds eight compounds (2b, 2c, 3b, 3c, 3f, 4a, 4b and 4c) have shown good hypoten

Cardiovascular effects of novel imidazoline congeners

2-Aryl-4,5-bis(diphenyl)-1-(N-acetyl hydrazide)-1,3-imidazoline (IIb1- 4) was prepared by the reaction of ethyl chloro acetate and hydrazine hydrate with 2-Aryl-4,5-bis (diphenyl) - 1H - imidazoline (I a1-4), which on further substitution with aryl/heterocyclyl aldheyde gave 2-Aryl-4,5-his (diphenyl)- 1-(4-substituted hydrazone) -1,3 - imidazoline (III Ca-1). This was again cyclised to oxadiazole in the presence of ferric chloride and glacial acetic acid yielded 2-Aryl-4,5-bis(diphenyl)-1-(2-substituted-1,3,4-oxadizole)-1,3- imidazoline (IV da-i). These compounds were screened for hypotensive activity and an attempt were made to get the site of action of these compounds.