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2551114-38-4

5-(dimethylphosphoryl)picolinonitrile is a chemical compound with the molecular formula C8H7N2O2P. It is a derivative of picolinonitrile, featuring a dimethylphosphoryl group attached to the 5-position of the picolinonitrile ring. 5-(dimethylphosphoryl)picolinonitrile is of interest in the field of organophosphorus chemistry and may have potential applications in the development of pesticides or as a chemical intermediate. The dimethylphosphoryl group imparts unique reactivity and properties to the molecule, which can be exploited in various chemical transformations and reactions.

2551114-38-4

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2551114-38-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2551114-38-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,5,5,1,1,1 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2551114-38:
(9*2)+(8*5)+(7*5)+(6*1)+(5*1)+(4*1)+(3*4)+(2*3)+(1*8)=134
134 % 10 = 4
So 2551114-38-4 is a valid CAS Registry Number.

2551114-38-4Downstream Products

2551114-38-4Relevant articles and documents

Phosphine Oxides (-POMe2) for Medicinal Chemistry: Synthesis, Properties, and Applications

Stambirskyi, Maksym V.,Kostiuk, Tetiana,Sirobaba, Serhii I.,Rudnichenko, Alexander,Titikaiev, Dmytro L.,Dmytriv, Yurii V.,Kuznietsova, Halyna,Pishel, Iryna,Borysko, Petro,Mykhailiuk, Pavel K.

, p. 12783 - 12801 (2021/09/18)

A general practical approach to hetero(aromatic) and aliphatic P(O)Me2-substituted derivatives is elaborated. The key synthetic step was a [Pd]-mediated C-P coupling of (hetero)aryl bromides/iodides with HP(O)Me2. The P(O)Me2 substituent was shown to dramatically increase solubility and decrease lipophilicity of organic compounds. This tactic was used to improve the solubility of the antihypertensive drug prazosin without affecting its biological profile.

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