25529-31-1Relevant academic research and scientific papers
Basic proline-amide derivatives of GE 2270 and GE 2270-like antibiotics
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, (2008/06/13)
PCT No. PCT/EP96/00407 Sec. 371 Date Jul. 31, 1997 Sec. 102(e) Date Jul. 31, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/24607 PCT Pub. Date Aug. 15, 1996The present invention refers to basic amides derivatives of GE 2270 and GE 2270-like antibiotics of general formula (1), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria.
Derivatives of antibiotic GE2270 factors C2a, D2 and E
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, (2008/06/13)
Mono- or di-substituted derivatives of GE2270 factors C2a, D2 and E of general formula (I), wherein W represents a moiety of formula (a), (b) or (c), R1 and R2 representing a variety of substituents, X1 is methyl, X2 is a --CH2 --W1 moiety and X3 is methylamino or amino, or X1 is a --CH2 --W1 moiety, X2 is methoxymethylene and X3 is methylamino, with the proviso that when X3 is amino, then W must be 2-(aminocarbonyl)-pyrrolidinyl; with the further proviso that when W is 2-(aminocarbonyl)-pyrrolidinyl, then W1 cannot be hydroxy; and the pharmaceutically acceptable salts thereof. The mono- or di-substituted derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria. STR1
Basic oxazoline-amide derivatives of GE2270 and GE2270-like antibiotics
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, (2008/06/13)
The present invention refers to basic oxazoline-amide derivatives of GE 2270 and GE 2270-like antibiotics of general formula (I), wherein the group GE represents the antibiotic core molecule. The amide derivatives of antibiotic GE 2270 of formula (I) are antimicrobial agents mainly active against gram positive bacteria. STR1
