2554-82-7

Usage

Uses

Used in Organic Synthesis:
2-Acetoxy-3-methoxybenzoic acid is used as a building block in organic synthesis for the creation of various chemical compounds. Its unique structure allows for the formation of a wide range of derivatives, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
As an intermediate in the production of pharmaceuticals, 2-acetoxy-3-methoxybenzoic acid plays a crucial role in the synthesis of various drugs. Its presence in the molecular structure of these drugs contributes to their therapeutic properties and effectiveness in treating different medical conditions.
Used in Agrochemical Production:
2-Acetoxy-3-methoxybenzoic acid is also utilized as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties enable the development of effective compounds for agricultural applications, helping to protect crops and enhance yield.
Used in Anti-Inflammatory and Analgesic Applications:
2-Acetoxy-3-methoxybenzoic acid has been investigated for its potential anti-inflammatory and analgesic properties. Its ability to modulate inflammatory responses and alleviate pain makes it a promising candidate for the development of new medications in these therapeutic areas.

InChI:InChI=1/C10H10O5/c1-6(11)15-9-7(10(12)13)4-3-5-8(9)14-2/h3-5H,1-2H3,(H,12,13)

Upstream product

• 877-22-5 3-methoxysalicylic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 65547-59-3 8-methoxy-2-methyl-4H-1-benzopyran-4-one 
• 367526-67-8 ethyl 8-methoxy-2-methyl-4-oxo-4H-benzopyran-3-carboxylate 
• 1313886-74-6 (2-hydroxy-3-methoxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 46984-64-9 2-hydroxy-3-methoxy-benzoic acid-(2-diethylamino-ethyl ester) 
• 218923-45-6 2'-deoxy-2'-(3-methoxy-2-acetoxybenzamido)-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)adenosine 
• 1053263-61-8 N-[(2R,3R,3aS,9aR)-2-(6-Amino-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl]-2-hydroxy-3-methoxy-benzamide 
• 770719-75-0 ethyl [(2-acetoxy-3-methoxyphenyl)hydroxymethylidene]acetylacetate 
• 367526-60-1 ethyl [(2-acetoxy-3-methoxyphenyl)hydroxymethylidene]ethoxycarbonylacetate 
• 58778-45-3 2-(chlorocarbonyl)-6-methoxyphenyl acetate 

Relevant academic research and scientific papers

Thiazole compound as well as preparation method and application thereof

The invention relates to thiazole compounds as well as a preparation method and application thereof, and belongs to the field of medicinal chemistry. The compound has a structural general formula described in the specifications of the invention; the compound or the prodrug thereof or pharmaceutically acceptable salts of the compound not only can significantly improve the biological activity, but also can effectively reduce the loss of biological activity due to glycosylation, significantly improve the exposure of effective drugs, and can be used for preparing medicines for preventing or treating hepatic fibrosis, medicines for preventing or treating viral influenza, medicines for treating Alzheimer's disease and Parkinson's disease and the like, and the clinical application of the compound is expanded.

Novel short-step synthesis of functionalized γ-phenyl-β- hydroxybutenoates and their cyclization to 4-hydroxycoumarins via the N-hydroxybenzotriazole methodology

A novel method for the synthesis of functionalized 3-substituted 4-hydroxycoumarins is reported. C-Acylation compounds were derived from the reaction of the N-hydroxybenzotriazole ester of the functionalized acetyl salicylic acids and a variety of active methylene compounds and cyclized to the title compounds. The synthesis is simple and the compounds are produced in yields varying from 39 to 80%. The structure of the newly prepared C-acylation compounds was thoroughly studied through NMR spectroscopy for the first time in the literature.

A highly practical route to 2-methylchromones from 2-acetoxybenzoic acids

2-Methylchromones were accessed via a keto ester condensation on 2-acetoxybenzoyl chloride, followed by cyclization and decarboxylation. No column chromatography was required in the process.

Substituted 2-amino chromones and process for the preparation thereof

This invention relates to substituted 2-amino chromones of the general structure I: SPC1 wherein R1, R2, R3, and R4 may be hydrogen, hydroxy, lower alkyl or lower alkoxy of 1-6 carbon atoms, halogen such as chloro or bromo, or aryl such as phenyl, and X may be cyano or carboxamido. Two novel procedures for preparing substituted 2-amino chromones having the Formula I, starting with salicylic acid or substituted salicylic acid, are described. The compounds of this invention are active in the prevention of allergic and asthmatic reactions in mammals.