2554-82-7

Basic information

• Product Name: 2-ACETOXY-3-METHOXYBENZOIC ACID
• Synonyms: RARECHEM AL BE 0818;ACETYL O-VANILLIC ACID;2-ACETOXY-3-METHOXYBENZOIC ACID
• CAS NO: 2554-82-7
• Molecular Formula: C₁₀H₁₀O₅
• Molecular Weight: 210.18
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 2554-82-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 324.259 °C at 760 mmHg
• Flash Point: 126.314 °C
• Appearance: /
• Density: 1.285 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: 2-ACETOXY-3-METHOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETOXY-3-METHOXYBENZOIC ACID(2554-82-7)
• EPA Substance Registry System: 2-ACETOXY-3-METHOXYBENZOIC ACID(2554-82-7)

Safety Data

• Hazardous Substances Data: 2554-82-7(Hazardous Substances Data)

Usage

General Description

2-Acetoxy-3-methoxybenzoic acid is a chemical compound with the molecular formula C10H10O5. It is a derivative of benzoic acid, with additional acetoxy and methoxy functional groups attached to the benzene ring. 2-ACETOXY-3-METHOXYBENZOIC ACID is commonly used as a building block in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. It has also been investigated for its potential anti-inflammatory and analgesic properties. The presence of both acetoxy and methoxy groups in its structure makes 2-acetoxy-3-methoxybenzoic acid a versatile and valuable compound for various chemical and medicinal applications.

InChI:InChI=1/C10H10O5/c1-6(11)15-9-7(10(12)13)4-3-5-8(9)14-2/h3-5H,1-2H3,(H,12,13)

Upstream product

• 877-22-5 3-methoxysalicylic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 58778-45-3 2-(chlorocarbonyl)-6-methoxyphenyl acetate 
• 1313886-74-6 (2-hydroxy-3-methoxyphenyl)(2-(4-methoxyphenyl)-5-methylbenzofuran-3-yl)methanone 
• 46984-64-9 2-hydroxy-3-methoxy-benzoic acid-(2-diethylamino-ethyl ester) 
• 218923-45-6 2'-deoxy-2'-(3-methoxy-2-acetoxybenzamido)-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)adenosine 
• 1053263-61-8 N-[(2R,3R,3aS,9aR)-2-(6-Amino-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl]-2-hydroxy-3-methoxy-benzamide 
• 367526-67-8 ethyl 8-methoxy-2-methyl-4-oxo-4H-benzopyran-3-carboxylate 
• 65547-59-3 8-methoxy-2-methyl-4H-1-benzopyran-4-one 
• 770719-75-0 ethyl [(2-acetoxy-3-methoxyphenyl)hydroxymethylidene]acetylacetate 
• 367526-60-1 ethyl [(2-acetoxy-3-methoxyphenyl)hydroxymethylidene]ethoxycarbonylacetate 

Relevant articles and documents

Thiazole compound as well as preparation method and application thereof

The invention relates to thiazole compounds as well as a preparation method and application thereof, and belongs to the field of medicinal chemistry. The compound has a structural general formula described in the specifications of the invention; the compound or the prodrug thereof or pharmaceutically acceptable salts of the compound not only can significantly improve the biological activity, but also can effectively reduce the loss of biological activity due to glycosylation, significantly improve the exposure of effective drugs, and can be used for preparing medicines for preventing or treating hepatic fibrosis, medicines for preventing or treating viral influenza, medicines for treating Alzheimer's disease and Parkinson's disease and the like, and the clinical application of the compound is expanded.

A highly practical route to 2-methylchromones from 2-acetoxybenzoic acids

2-Methylchromones were accessed via a keto ester condensation on 2-acetoxybenzoyl chloride, followed by cyclization and decarboxylation. No column chromatography was required in the process.