25542-86-3

Usage

Uses

Used in Cleaning Products:
Sodium (2-hexyldecyl) sulphate is used as a foaming and cleansing agent in cleaning products for its ability to create a rich lather and effectively remove dirt and grease.
Used in Personal Care Products:
In personal care products, sodium (2-hexyldecyl) sulphate is used as an emulsifying agent in shampoos, body washes, and other formulations to help blend oil and water components, ensuring a smooth and consistent texture.
Used in Dish Detergents:
Sodium (2-hexyldecyl) sulphate is used as a surfactant in dish detergents to lower the surface tension of water, allowing it to penetrate and lift away grease and food particles from dishes and utensils.
Safety Considerations:
While sodium (2-hexyldecyl) sulphate is generally regarded as safe for use in products intended for consumer use, it should be handled with caution and kept out of reach of children to prevent accidental ingestion or exposure.

InChI:InChI=1/C16H34O4S.Na/c1-3-5-7-9-10-12-14-16(13-11-8-6-4-2)15-20-21(17,18)19;/h16H,3-15H2,1-2H3,(H,17,18,19);/q;+1/p-1

Upstream product

• 2425-77-6 2-hexyldecan-1-ol 

Relevant academic research and scientific papers

API ionic liquids: Probing the effect of counterion structure on physical form and lipid solubility

Lipid based formulations (LBFs) are extensively utilised as an enabling technology in drug delivery. The use of ionic liquids (ILs) or lipophilic salts (LS) in drug delivery has also garnered considerable interest due to unique solubility properties. Conversion of active pharmaceutical ingredients (API) to ILs by pairing with an appropriately lipophilic counterion has been shown to decrease melting point of the salt complex and improve solubility in LBFs. However, the relationship between the structure of the counterion, the physicochemical properties of the resulting salts and solubility in LBFs has not been systematically explored. This study investigates the relationship between alkyl sulfate counterion structure and melting temperature (Tm or Tg) in addition to LBF solubility, utilizing cinnarizine and lumefantrine as model weakly basic APIs. Three series of structurally diverse alkyl sulfate counterions were chosen to probe this relationship. Pairing cinnarizine and lumefantrine with a majority of these alkyl sulfate counterions resulted in a reduction in melting temperature and enhanced solubility in model medium chain and long chain LBFs. The chain length of the alkyl sulfate plays a crucial role in performance, and consistently branched alkyl sulfate counterions perform better than straight chain alkyl sulfate counterions, as predicted. Most interestingly, trends in counterion performance were found to be consistent across two APIs with disparate chemical structures. The findings from this study will facilitate the design of counterions which enhance solubility of ionisable drugs and unlock the potential to develop compounds previously restrained by poor solubility.

Fundamental Interfacial Properties of Alkyl-Branched Sulfate and Ethoxy Sulfate Surfactants Derived from Guerbet Alcohols. 1. Surface and Instantaneous Interfacial Tensions

Guerbet surfactants are a unique class of amphiphiles in which the carbon atom β to the head group carries an alkyl substituent.A variety of Guerbet sulfate and monodispers ethoxy sulfate surfactants were synthesized, and their interfacial properties determined at the air-water and decane-water interfaces to determine how Guerbet branching influences interfacial properties.Guerbet surfactants exhibited higher critical micelle concentrations and enhanced effectiveness and efficiency in lowering the surface tension at the air-water interface compared to their linear counterparts.At the decane-water interface the differences between the Guerbet and linear surfactants were not as pronounced as at the air-water interface.The relationship between Guerbet hydrophobe structure and interfacial properties is discussed.