25543-10-6

Basic information

• Product Name: 1,3-Dioxo-2-isoindolinecarboxylic acid methyl ester
• Synonyms: 1,3-Dioxo-2-isoindolinecarboxylic acid methyl ester;N-(Methoxycarbonyl)phthalimide;methyl 1,3-dioxoisoindoline-2-carboxylate;Methyl 1,3-dioxoisoindole-2-carboxylate
• CAS NO: 25543-10-6
• Molecular Formula: C₁₀H₇NO₄
• Molecular Weight: 205.17
• Mol File: 25543-10-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxo-2-isoindolinecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxo-2-isoindolinecarboxylic acid methyl ester(25543-10-6)
• EPA Substance Registry System: 1,3-Dioxo-2-isoindolinecarboxylic acid methyl ester(25543-10-6)

Safety Data

• Hazardous Substances Data: 25543-10-6(Hazardous Substances Data)

Usage

Type of compound

Methyl ester derivative

Parent compound

1,3-dioxo-2-isoindolinecarboxylic acid

Common use

Synthesis of pharmaceuticals and organic compounds

Field of application

Medicinal chemistry

Known for

Modifying and influencing biological activities of drug molecules

Health and environmental risks

Potential risks if not properly managed

Importance

Diverse applications in pharmaceutical and chemical industries

Upstream product

• 1074-82-4 potassium phtalimide 
• 79-22-1 methyl chloroformate 
• 136918-14-4 phthalimide 

Downstream Products

• 96561-36-3 L-threo-(N-phthaloyl-3-(3,4-methylenedioxyphenyl)serine) norephedrine salt 
• 96561-34-1 (2S,3R)-3-(benzo[d][1,3]dioxol-5-yl)-2-(1,3-dioxoisoindolin-2-yl)-3-hydroxypropanoic acid 
• 96561-53-4 L-threo-(N-phthaloyl-3-(3,4-dihydroxyphenyl)serine) 
• 1458647-14-7 2-phthalimido-3-hydroxy-3-(3,4-methylenedioxyphenyl)propionic acid 
• 94830-01-0 2-{4-[(2-Methoxy-4-nitro-phenyl)-hydrazono]-butyl}-isoindole-1,3-dione 
• 94829-99-9 2-methoxy-5-nitrophenylhydrazone of γ-phtalimidobutyraldehyde 
• 94830-00-9 2-{4-[(4-Methoxy-2-nitro-phenyl)-hydrazono]-butyl}-isoindole-1,3-dione 
• 94830-02-1 2-{4-[(4-Chloro-2-nitro-phenyl)-hydrazono]-butyl}-isoindole-1,3-dione 
• 112452-76-3 Toluene-4-sulfonic acid 3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-1-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-propyl ester 

Relevant articles and documents

METHOD OF DROXIDOPA SYNTHESIS

The present application relates to a novel method of preparing L-threo-dihydroxyphenylserine (droxidopa). Specifically, the application is directed to a method of preparing droxidopa via a deprotection step that is an alternative to deprotection steps tha