25546-12-7

Upstream product

• 64-17-5 ethanol 
• 88-82-4 2,3,5-triiodobenzoic acid 

Downstream Products

• 524931-72-4 ethyl 2-acetyl-3,5-diiodobenzoate 
• 524931-70-2 ethyl 2-cyano-3,5-diiodobenzoate 
• 1221971-15-8 triethyl 5-iodobenzene-1,2,3-tricarboxylate 
• 1309459-50-4 3-(5,7-diiodo-3-oxo-1,3-dihydroisobenzofuran-1-yl)benzonitrile 
• 524931-86-0 ethyl 2-acetyl-3-benzoyl-5-iodobenzoate 
• 524931-87-1 ethyl 2-acetyl-3-(2-furoyl)-5-iodobenzoate 
• 524931-85-9 ethyl 2-acetyl-3-(cyclopropylcarbonyl)-5-iodobenzoate 
• 913187-98-1 ethyl 3-(2-fuoryl)-5-iodo-2-propionylbenzoate 

Relevant academic research and scientific papers

Successive iodine-magnesium or -copper exchange reactions for the selective functionalization of polyhalogenated aromatics

(Matrix presented) The presence of an electron-withdrawing group or chelating group was found to direct the halogen-copper and halogen-magnesium exchange with various di- or trihalogenated aromatics. Starting with a triiodobenzoate derivative, a range of

Regioselective Iodine/Zinc Exchange for the Selective Functionalization of Polyiodinated Arenes and Heterocycles in Toluene

Regioselective I/Zn-exchange reactions were performed on polyiodinated arenes or heterocycles within 20 minutes at 0-25 °C using the bimetallic combination pTol2Zn2LiOR [R = (CH2)2N(Me)(CH2)2NMe2] in toluene. The resulting diaryl- or diheteroarylzincs reacted well with allylic bromides and acyl chlorides to provide functionalized (hetero)- aryl iodides in good yields.