25557-76-0Relevant academic research and scientific papers
New γ-thiazolidine-1,3-dithiolanes as radioprotectors
Law, Ho.,Pera, M. H.,Taillandier, G.,Fatome, M.,Laval, J. D.,Leclerc, G.
, p. 121 - 126 (2007/10/02)
Fourteen γ-thiazolidine-1,3-dithiolanes were prepared and tested as radioprotective agents.The combination within a single molecule of thiazolidine and dithiolane moieties, both of which are known for their radioprotective properties, was achieved for the first time.Several molecules show significant radioprotective activity: immediate 4l; delayed 4b, 4f, 4h; or immediate and prolonged 4a. dithiolanes / thiazolidines / radioprotectors / LD50 30 days
