25573-43-7

Usage

Uses

Used in Pharmaceutical Industry:
Eseridine is used as a therapeutic agent for its potential medicinal properties. It is recognized for its ability to interact with biological systems, making it a promising candidate for the development of new drugs and treatments.
Used in Chemical Research:
In the field of chemical research, eseridine serves as a crucial reagent for studying various biological processes and mechanisms. Its unique structure allows scientists to explore its potential in understanding complex interactions within living organisms.
Used in Drug Development:
Eseridine is utilized in the development of new drugs due to its therapeutic potential. Its properties make it a valuable compound for designing and synthesizing novel pharmaceuticals that can target specific biological pathways or diseases.
Used in Biological Studies:
Eseridine is employed in biological studies to investigate the mechanisms of various diseases and conditions. Its unique structure and properties enable researchers to gain insights into the underlying causes of these health issues and develop targeted treatments.

InChI:InChI=1/C15H21N3O3/c1-15-7-8-17(3)21-13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15-/m1/s1

Upstream product

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• 105780-79-8 3-allyl-5-hydroxy-1,3-dimethylindol-2(3H)-one 
• 102616-00-2 methyl (2-(1-(hydroxymethyl)-1-methyl-3-butenyl)-4-methoxyphenyl)carbamate 
• 102615-91-8 3-allyl-1-carbomethoxy-5-methoxy-3-methyloxindole 
• 102615-99-6 2-(bromomethyl)-4-(2-((methoxycarbonyl)amino)-5-methoxyphenyl)-4-methyltetrahydrofuran 
• 102615-97-4 2-(bromomethyl)-4-(2-carboxy-5-methoxyphenyl)-4-methyltetrahydrofuran 
• 102615-95-2 2-(bromomethyl)-4-(2-(hydroxymethyl)-5-methoxyphenyl)-4-methyltetrahydrofuran 
• 102615-96-3 2-(bromomethyl)-4-(2-formyl-5-methoxyphenyl)-4-methyltetrahydrofuran 
• 102615-90-7 4-allyl-6-methoxy-4-methylisochroman-3-one 
• 105780-80-1 3-allyl-1,3-dimethyl-5-(N-methylcarbamoyloxy)indol-2(3H)-one 
• 105780-78-7 3-allyl-1,3-dimethyl-5-methoxy-2-oxo-1,3-dihydroindole 

Relevant academic research and scientific papers

Application of a Tandem Electrocyclic Sigmatropic Reaction of o-Quinodimethane to the Synthesis of Calabar Bean Alkaloids. Part 2. First Total Synthesis of (+/-)-Geneserine

The first total synthesis of the Calabar bean alkaloid geneserine (1) starting with 1-cyano-5-methoxybenzocyclobutene (7) has been accomplished via a 16 step sequence in 27percent overall yield.The key step in the synthetic strategy involves the tandem electrocyclic sigmatropic reaction of the o-quinodimethane generated in situ by thermolysis of the benzocyclobutene (4), which affords quantitatively the isochroman-3-one (5).After the conversion of (5) into the oxindole (6), the pivotal intermediate for our strategy, differential functionalisation of this system provides the hydroxylamine (19) which has finally been converted into (+/-)-geneserine by treatment with di-isobutylaluminium hydride.

The Total Synthesis of (+/-)-Geneserine

The first total synthesis of (+/-)-geneserine was achieved from the oxindole (2), which was efficiently prepared from the benzocyclobutene (4) via the tandem electrocyclic sigmatropic methodology.