255818-54-3Relevant articles and documents
Synthesis of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides as potential antiviral agents
Cavalcanti, Socrates C. H.,Xiang, Yuejun,Newton, M. Gary,Schinazi, Raymond F.,Cheng, Yung-Chi,Chu, Chung K.
, p. 2233 - 2252 (2007/10/03)
A series of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides has been synthesized as potential antiviral agents. The synthesized compounds were evaluated against HIV-1, HBV, HSV-1, and HSV-2. Among the synthesized analogues, only the cytosine derivative showed moderate antiviral activity against HIV and HBV.