25589-18-8Relevant articles and documents
Direct Chemoselective Synthesis of N-3-Substituted Pyrimidinones in a Microwave-Assisted Method
Laxminarayana, Burgula,Kundu, Lal Mohan
supporting information, p. 1342 - 1353 (2015/05/26)
Synthesis of selectively N-3-substituted pyrimidine nucleobases or pyrimidinones has always been a challenge because of poor regioselectivity and chemoselectivity. In this article we demonstrate a single-step, de novo synthesis of selectively N-3-substitu
Heterocyclic Transformations. Part 6. Studies on the Reactions of 3-Benzyl-6-methyl-1,3-oxazine-2,4(3H)-dione with α-Amino and Hydroxy Amides
Singh, Harjit,Singh, Palwinder,Chimni, Swapandeep Singh,Kumar, Subodh
, p. 364 - 365 (2007/10/03)
Amide nitrogen-induced reactions of α-amino and hydroxy amides with 3-benzyl-6-methyl-1,3-oxazine-2,4(3H)-dione 1 give 6-substituted-5-acetyluracils 2; a competitive reaction initiated by the amine nitrogen of an amino amide in some cases also yields 1-su
A useful methodology for the regioselective deprotection of 1,3-dibenzyluracils
Botta,Summa,Saladino,Nicoletti
, p. 2181 - 2187 (2007/10/02)
A practical, regioselective N-1 deprotection of 1,3-dibenzyl uracils 2 a-e is described. The same experimental procedure and longer reaction time afforded the complete deprotection of the uracils.