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1-{4-[N-(pyridin-3-ylmethoxycarbonyl)-aminomethyl]benzoyl}imidazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

255894-58-7

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255894-58-7 Usage

Complex molecule

The chemical is a complex molecule with multiple functional groups and structural elements.

Benzoyl functional group

The molecule contains a benzoyl functional group, which is an aromatic ring with a carbonyl group attached.

Imidazole functional group

The molecule also contains an imidazole functional group, which is a five-membered ring with two nitrogen atoms.

Pyridine ring

The chemical includes a pyridine ring, which is a six-membered aromatic ring with one nitrogen atom.

Aminomethyl group

The molecule has an aminomethyl group, which is a methyl group with an amine (-NH2) attached.

Methoxycarbonyl moiety

The compound contains a methoxycarbonyl moiety, which is a carbonyl group with a methoxy (-OCH3) group attached.

Potential pharmaceutical applications

The chemical may have potential pharmaceutical applications due to its structural elements and functional groups that could interact with biological targets.

Interaction with biological targets

The presence of various functional groups and structural elements in the molecule suggests that it could potentially interact with biological targets, such as enzymes or receptors.

Further research needed

To fully understand the properties and potential uses of 1-{4-[N-(pyridin-3-ylmethoxycarbonyl)-aminomethyl]benzoyl}imidazole in the pharmaceutical and chemical industries, further research would be required.

Structural complexity

The molecule's structural complexity, with multiple functional groups and structural elements, may contribute to its potential pharmaceutical applications and interactions with biological targets.

Check Digit Verification of cas no

The CAS Registry Mumber 255894-58-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,5,8,9 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 255894-58:
(8*2)+(7*5)+(6*5)+(5*8)+(4*9)+(3*4)+(2*5)+(1*8)=187
187 % 10 = 7
So 255894-58-7 is a valid CAS Registry Number.

255894-58-7Downstream Products

255894-58-7Relevant academic research and scientific papers

Method of producing benzamide derivatives

-

, (2008/06/13)

In the case that a selectively monoacylated phenylenediamine derivative which is useful as any of medicines, agricultural chemicals, animal drugs and the intermediates of chemicals is prepared by reacting a benzoic acid derivative with a phenylenediamine derivative, the benzoic acid derivative is converted into a benzoyl imidazole derivative and this benzoyl imidazole derivative is then reaction with the phenylenediamine derivative, whereby the improvement of a preparation efficiency and the high selectivity of the monoacylation can be achieved, the steps of protection and deprotection being omitted.

Synthesis and histone deacetylase inhibitory activity of new benzamide derivatives

Suzuki, Tsuneji,Ando, Tomoyuki,Tsuchiya, Katsutoshi,Fukazawa, Nobuyuki,Saito, Akiko,Mariko, Yukiyasu,Yamashita, Takashi,Nakanishi, Osamu

, p. 3001 - 3003 (2007/10/03)

Newly synthesized benzamide derivatives were evaluated for their inhibitory activity against histone deacetylase. The structure of these derivatives was unrelated to the known inhibitors, and IC50 values of the active compounds were in the range of 2-50 μM. Structure-activity relationship on the benzanilide moiety showed that the 2'-substituent, an amino or hydroxy group, was indispensable for inhibitory activity. Although the electronic influence of the substituent in the anilide moiety showed only a small effect on inhibitory activity, the steric factor in the anilide moiety, especially at positions 3'and 4', played an important role in interaction with the enzyme. Among these benzamide derivatives, MS-275 (1), which showed significant antitumor activity in vivo, has been selected for further investigation.

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