255897-08-6Relevant academic research and scientific papers
Asymmetric synthesis of conformationally constrained 4-hydroxyprolines and their applications to the formal synthesis of (+)-epibatidine
Avenoza, Alberto,Cativiela, Carlos,Fernandez-Recio, Miguel A.,Peregrina, Jesus M.
, p. 3999 - 4007 (2007/10/03)
This report describes the synthesis of enantiomerically pure (1S,3S,4R)- and (1S,3R,4R)-3-hydroxy-7-azabicyclo[2.2.1]heptane-1-carboxylic acids, two new conformationally constrained 4-hydroxyprolines, using a straightforward synthetic route and starting f
